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- W131294005 abstract "This chapter discusses the mechanisms of immunity in bacterial infections. The adaptation of pathogens to survival in phagocytes is crucial to determining the kind of immune response that confers protection. Opsonization of bacteria is mediated principally through specific immunoglobulin G antibodies or complement factors C3b and C4b. Resistance to intracellular parasites, capable of surviving in phagocytes, hinges upon a cell-mediated immune response in which immune T cells bring about proliferation, aggregation, and activation of macrophages. Mucous membranes are the site of many bacterial infections and the principal portals of entry through which pathogens invade the body and produce generalized disease. Immobilization can be brought about by antibodies in each of the major classes. Variation in the surface structure of a microorganism represents a highly effective means of thwarting the immune response, in that antibodies or immune T cells produced against the infecting strain become ineffective. Antibodies on mucous membranes play an important selective role in regulating indigenous bacterial flora. Antibody coating inhibits adherence and thereby limits or prevents colonization." @default.
- W131294005 created "2016-06-24" @default.
- W131294005 creator A5052526786 @default.
- W131294005 date "1979-01-01" @default.
- W131294005 modified "2023-10-14" @default.
- W131294005 title "Mechanisms of Immunity in Bacterial Infections" @default.
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- W131294005 doi "https://doi.org/10.1016/b978-0-12-039223-0.50009-3" @default.
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