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• W131490258 abstract "Descriptions of cerebral energy requirements found in the literature may confuse many readers. On one hand, Hawkins (1) states that, “Although nervous tissue does not participate in processes that require large amounts of energy, such as mechanical work, osmotic work, or extensive biosynthesis, it has almost as high a rate of oxidative metabolism as some tissues that do.” On the other, Clarke and Sokoloff (2) assert that, “Although it is sometimes stated that the brain is unique among tissues in its high rate of oxidative metabolism, the overall cerebral metabolic rate for 02 (CMRO2) is of the same order as the unstressed heart and renal cortex.” These two contrasting views are not necessarily contradictory. Whether or not the brain has higher energy requirements than other tissues, the brain is unique, both in its energy-demanding functions and the limitations on the types of fuels it uses and their routes of delivery. The above statements are also indicative of the reason brain-energy metabolism has developed into a separate specialty, in which the energy supply and demand of the brain are studied as the basis for many brain dysfunctions and disorders. The past 15 years witnessed several discoveries and new developments in the field of cerebral energy metabolism, which could explain some of the brain’ s unique energy requirements, and provide a better understanding of various brain disorders." @default.
• W131490258 created "2016-06-24" @default.
• W131490258 creator A5029976912 @default.
• W131490258 date "2002-01-01" @default.
• W131490258 modified "2023-09-23" @default.
• W131490258 title "Neuronal Energy Requirements" @default.
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• W131490258 doi "https://doi.org/10.1007/978-1-59259-108-4_2" @default.
• W131490258 hasPublicationYear "2002" @default.
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