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- W131728785 abstract "INTRODUCTION: The statistical model SONOBREAST can predict the risk of malignancy in breast masses, based on sonographic features, patient’s age and family history. Nonetheless, in the original study, most of the women were from public hospitals, having a low socioeconomic level and usually big palpable tumors.OBJECTIVE: Validate the SONOBREAST in women from the private office, with a different epidemiologic profile and compare it to the standard BIRADS system. METHODOLOGY: There were included prospectively 500 solid masses visible on ultrasound, from 274 women from the private office, that presented any indication of surgery and that agreed to participate in the study. The sonographic characteristics, the age of the women, and the first degree family history were recorded in a formulary. The probability of malignancy was calculated according to the SONOBREAST model, in the website, www. sonobreast.com, and according to the BIRADS system. The results were compared to the anatomopathological examination. For the statistic analysis, it was used the SPSS program, version 11.0.1.RESULTS: The mean age was 41.92 (+14.40) years-old. There were 87 (17.40%) malignant tumors. There were 382 (76.40%) nonpalpable masses. The mean size of the lesions was 16.34 (+8.73) mm. If it was considered suspicious any lesion above the level 2%, like in the BIRADS system, the SONOBREAST presented a sensibility of 95.40%, specificity of 78.69%, positive predictive value of 48.54%, negative predictive value of 98.78% and accuracy of 81.60%, that was identical to the BIRADS (kappa = 1,00, p < 0,001). The area under de ROC curve for the individualized probabilities of malignancy calculated by the SONOBREAST was 94.41% (92.20-96.62), and, by the BIRADS system, it was 89.99 (86.60-93.37).CONCLUSION: The SONOBREAST can be used to calculate the probability of malignancy in solid breast masses, visible on ultrasound, in a very precise and accurate way, also for women from the private office. Its accuracy is identical to the standard BIRADS system, when using the same cutoff parameters." @default.
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- W131728785 date "2012-10-10" @default.
- W131728785 modified "2023-09-25" @default.
- W131728785 title "Validation of the Statistical Model Sonobreast in Predicting Malignancy for Sonographic Visible Masses in Patients of the Private Office" @default.
- W131728785 doi "https://doi.org/10.7170/jsis.v1i3.333" @default.
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