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- W132724712 abstract "Indol-3-ylpyruvic acid (IPA, 10-100 mg/kg), an endogenous metabolite of tryptophan, shortened ethanol anaesthesia in C57Bl/6 male mice and diminished the post-ethanol (23 hr) inhibition of locomotion. In an elevated plus-maze, IPA had an anxiolytic effect in short-sleep, but not in long-sleep, mice. IPA did not modify ethanol-induced or caffeine-induced stimulation of spontaneous locomotion or the anxiogenic effect of pentylenetetrazole in an elevated plus-maze. The probable involvement of IPA in the defence mechanisms in alcoholism is suggested." @default.
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- W132724712 date "1994-05-01" @default.
- W132724712 modified "2023-09-27" @default.
- W132724712 title "ANTIETHANOL EFFECTS OF INDOL-3-YLPYRUVIC ACID IN MICE" @default.
- W132724712 doi "https://doi.org/10.1093/oxfordjournals.alcalc.a045533" @default.
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