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- W132871910 abstract "Case summary Mrs C.A. is 30-year-old Caucasian woman with mental disability and bipolar disorder type I. In October 2013, she presented with very severe behavioural abnormalities and was treated with intensification of therapy with quetiapine 300 mg TID, haloperidol 4 mg TID, paliperidone 6 mg OD, and fluphenazine decanoate 25 mg i.m. once every 21 days, clonazepam 1 mg OD and lorazepam 2.5 mg OD. In December 2013 extrapyramidal effects developed and hospital admission was necessary. Neuroleptic therapy was immediately stopped. After a few days, fever appeared with consciousness disorders and high levels of creatine kinase. Laboratory tests and imaging studies with negative results were performed. A diagnosis of NMS was made and she received supportive and specific therapy with dantrolene, diazepam, baclofen, rotigotine and L-Dopa. After 3 months, Mrs. C.A. survived NMS but she showed chronic rigidity and mutism. She was transferred to an intensive neurorehabilitation centre." @default.
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- W132871910 date "2015-03-01" @default.
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- W132871910 title "Severe long term chronic complications of neuroleptic malignant syndrome: a case report" @default.
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