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- W132912267 abstract "The authors recommend paracetamol as first-line treatment as well as long-term treatment for symptomatic osteoarthritis of the knee, in accordance with the analgesic/therapeutic guideline set out by EULAR. In 30 years of clinical practice, I have found paracetamol almost completely ineffective for arthritis pain. Non-steroidal anti-inflammatory drugs (NSAIDs) were notably more effective, if necessary in combination with proton pump inhibitors and for short-term combination treatment with metamizole. At low dosages, NSAIDs have a low side effect profile, even during long-term treatment. With paracetamol, there is a risk of liver damage if maximum doses are taken regularly. This is one of the reasons why paracetamol is now available on prescription only. In own my clinical practice, intra-articular injection of a steroid has always proved the best treatment for acute severe pain." @default.
- W132912267 created "2016-06-24" @default.
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- W132912267 date "2010-08-30" @default.
- W132912267 modified "2023-09-25" @default.
- W132912267 title "Almost Ineffective" @default.
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- W132912267 doi "https://doi.org/10.3238/arztebl.2010.0602a" @default.
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