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- W132970124 abstract "A pilot study was conducted in an endemic village for bancroftian filariasis to find out thecompliance and antifilarial action of large doses of mebendazole (30 mg/kg/day). Thirtyeight patients with early clinical filariasis and 16 with asymptomatic microfilaraemiawere treated, under supervision. ‘The compliance for drug consumption was high andthere were no serious adverse reactions. Majority of the side effects were gastrointestinaland mild. The drug, in combination with diethylcarbamazine (DEC), showed microfilaricidaleffect, but the effect was similar to that seen with DEC alone. In as many as 5 ofthe 13, who were followed at 1 yr, microfilaria persisted at the end of 1 yr, though with areduced density. Prolonged (1 yr) treatment with mebendazole in combination with DECdid not have a beneficial effect in most patients with clinical disease." @default.
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- W132970124 date "1988-06-01" @default.
- W132970124 modified "2023-09-30" @default.
- W132970124 title "Use of mebendazole in combination with DEC in bancroftian filariasis." @default.
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