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- W133026347 abstract "A stratified study is often designed for adjusting several independent trials in modern medical research. In this paper, we consider approximate sample size formulas for a non-unity relative risk in stratified matched-pair studies. To evaluate the accuracy and usefulness of these sample size formulae developed in this paper, we further calculate their simulated powers. Our empirical results confirm sample sizes formulae based on the constrained maximum likelihood estimation method can provide a sample size estimate that guarantees pre-specified power of a test at a given significance level. A real example from clinical studies is used to illustrate the proposed methodologies." @default.
- W133026347 created "2016-06-24" @default.
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- W133026347 date "2011-01-01" @default.
- W133026347 modified "2023-09-24" @default.
- W133026347 title "Sample Size Determination via Non-unity Relative Risk for Stratified Matched-Pair Studies" @default.
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- W133026347 doi "https://doi.org/10.1007/978-3-642-18387-4_54" @default.
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