FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W133030804> ?p ?o ?g. }

• W133030804 endingPage "890" @default.
• W133030804 startingPage "883" @default.
• W133030804 abstract "Flat revertants of v-ras-transformed (KNRK) rat kidney cells, which express elevated levels of p21ras protein, were generated to high efficiencies with sodium butyrate (NaB). Overall protein synthesis in revertants was not different from parental cells, although changes were evident in expression and distribution of specific microfilament-associated cytoskeletal proteins. Quantitative two-dimensional electrophoresis revealed revertant-associated 3-4-fold increases in cytoskeletal deposition of the microfilament-associated proteins gelsolin and vinculin correlating with microfilament reorganization and focal-contact formation respectively. Similar increases in actin content were evident at both the total-cellular- and cytoskeletal-associated-protein levels. In contrast, intermediate-filament family elements (vimentin, lamins) remained unaltered. The only unique protein resolved in flat revertants was p52, a 52 kDa extracellular-matrix-associated protein previously identified as plasminogen-activator inhibitor type 1 (PAI-1). p52(PAI-1) expression was induced early during generation of the revertant phenotype and preceded development of focal-contact structures. NaB-induced p52(PAI-1) synthesis and generation of early morphological reversion in KNRK cells required ongoing RNA synthesis, since exposure to actinomycin D before addition of NaB inhibited both events. p52(PAI-1) induction by NaB was regulated at the level of mRNA abundance; in contrast, actin mRNA levels were the same in parental and revertant cells, suggesting that the increased actin content which typified the revertant phenotype was due to augmented actin microfilament stability." @default.
• W133030804 created "2016-06-24" @default.
• W133030804 creator A5036216288 @default.
• W133030804 creator A5041777869 @default.
• W133030804 date "1991-11-01" @default.
• W133030804 modified "2023-09-27" @default.
• W133030804 title "p52(PAI-1) and actin expression in butyrate-induced flat revertants of v-ras-transformed rat kidney cells" @default.
• W133030804 cites W103682637 @default.
• W133030804 cites W1481872744 @default.
• W133030804 cites W1492555913 @default.
• W133030804 cites W1493779021 @default.
• W133030804 cites W1497695953 @default.
• W133030804 cites W1513154697 @default.
• W133030804 cites W1515078836 @default.
• W133030804 cites W1517536901 @default.
• W133030804 cites W1544945960 @default.
• W133030804 cites W1553627317 @default.
• W133030804 cites W1563205636 @default.
• W133030804 cites W1564829038 @default.
• W133030804 cites W1576287355 @default.
• W133030804 cites W1742358547 @default.
• W133030804 cites W1779241686 @default.
• W133030804 cites W1808538746 @default.
• W133030804 cites W1852383835 @default.
• W133030804 cites W1912630452 @default.
• W133030804 cites W1969560454 @default.
• W133030804 cites W1970232503 @default.
• W133030804 cites W1973366924 @default.
• W133030804 cites W1979641607 @default.
• W133030804 cites W1987954100 @default.
• W133030804 cites W2002613888 @default.
• W133030804 cites W2003015952 @default.
• W133030804 cites W2003197672 @default.
• W133030804 cites W2014086967 @default.
• W133030804 cites W2025069938 @default.
• W133030804 cites W2032148686 @default.
• W133030804 cites W2041614761 @default.
• W133030804 cites W2055088010 @default.
• W133030804 cites W2084004810 @default.
• W133030804 cites W2089693544 @default.
• W133030804 cites W2090625578 @default.
• W133030804 cites W2095204823 @default.
• W133030804 cites W2113210366 @default.
• W133030804 cites W2125561151 @default.
• W133030804 cites W2144125159 @default.
• W133030804 cites W2146643228 @default.
• W133030804 cites W2167948821 @default.
• W133030804 cites W2168098899 @default.
• W133030804 cites W2258848270 @default.
• W133030804 cites W227835496 @default.
• W133030804 cites W2311269672 @default.
• W133030804 cites W2415905438 @default.
• W133030804 doi "https://doi.org/10.1042/bj2790883" @default.
• W133030804 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1151528" @default.
• W133030804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1953684" @default.
• W133030804 hasPublicationYear "1991" @default.
• W133030804 type Work @default.
• W133030804 sameAs 133030804 @default.
• W133030804 citedByCount "24" @default.
• W133030804 crossrefType "journal-article" @default.
• W133030804 hasAuthorship W133030804A5036216288 @default.
• W133030804 hasAuthorship W133030804A5041777869 @default.
• W133030804 hasBestOaLocation W1330308042 @default.
• W133030804 hasConcept C104317684 @default.
• W133030804 hasConcept C105580179 @default.
• W133030804 hasConcept C125705527 @default.
• W133030804 hasConcept C142669718 @default.
• W133030804 hasConcept C147447768 @default.
• W133030804 hasConcept C1491633281 @default.
• W133030804 hasConcept C151166631 @default.
• W133030804 hasConcept C153911025 @default.
• W133030804 hasConcept C189040839 @default.
• W133030804 hasConcept C189165786 @default.
• W133030804 hasConcept C203014093 @default.
• W133030804 hasConcept C204232928 @default.
• W133030804 hasConcept C2777979848 @default.
• W133030804 hasConcept C55493867 @default.
• W133030804 hasConcept C62478195 @default.
• W133030804 hasConcept C78383274 @default.
• W133030804 hasConcept C80722340 @default.
• W133030804 hasConcept C86803240 @default.
• W133030804 hasConcept C95444343 @default.
• W133030804 hasConceptScore W133030804C104317684 @default.
• W133030804 hasConceptScore W133030804C105580179 @default.
• W133030804 hasConceptScore W133030804C125705527 @default.
• W133030804 hasConceptScore W133030804C142669718 @default.
• W133030804 hasConceptScore W133030804C147447768 @default.
• W133030804 hasConceptScore W133030804C1491633281 @default.
• W133030804 hasConceptScore W133030804C151166631 @default.
• W133030804 hasConceptScore W133030804C153911025 @default.
• W133030804 hasConceptScore W133030804C189040839 @default.
• W133030804 hasConceptScore W133030804C189165786 @default.
• W133030804 hasConceptScore W133030804C203014093 @default.
• W133030804 hasConceptScore W133030804C204232928 @default.
• W133030804 hasConceptScore W133030804C2777979848 @default.
• W133030804 hasConceptScore W133030804C55493867 @default.
• W133030804 hasConceptScore W133030804C62478195 @default.
• W133030804 hasConceptScore W133030804C78383274 @default.

• next