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- W133037644 abstract "Anterograde trafficking of newly synthesized G protein-coupled -receptors (GPCRs) from the endoplasmic reticulum to the cell surface represents a crucial checkpoint in controlling the amount of the functional receptors at the cell surface and the strength of signaling initiated by the receptors. In contrast to the extensively studied, well-understood endocytic and recycling pathways, the molecular mechanisms underlying the cell-surface targeting of the receptors remain poorly defined. In this chapter, I will discuss current advances in understanding post-Golgi transport of GPCRs by focusing on specific motifs or sequences that may function as sorting signals regulating export from the Golgi and subsequent transport to the plasma membrane of GPCRs." @default.
- W133037644 created "2016-06-24" @default.
- W133037644 creator A5008175920 @default.
- W133037644 date "2012-01-01" @default.
- W133037644 modified "2023-10-18" @default.
- W133037644 title "Regulation of Post-Golgi Traffic of G Protein-Coupled Receptors" @default.
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- W133037644 doi "https://doi.org/10.1007/978-94-007-4765-4_5" @default.
- W133037644 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3603137" @default.
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