Matches in SemOpenAlex for { <https://semopenalex.org/work/W133091976> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W133091976 endingPage "457" @default.
- W133091976 startingPage "452" @default.
- W133091976 abstract "Summary The role played by a hypercoagulable state, either inherited or acquired, in the pathogenesis of upper-extremity deep vein thrombosis (UEDVT) remains a question of debate. We performed a case-control study including 79 patients with a first objectively confirmed episode of UEDVT, 31 secondary and 48 primary, and 165 healthy controls. Nine patients (11.4%) with UEDVT were carriers of the prothrombin G20210A mutation vs. six (3.7%) in controls; P = 0.025, OR: 3.39 (95% CI 1.16 to 9.88). No statistical difference was observed between cases and controls for the factor V Leiden mutation, AT, protein C or protein S deficiency and anticardiolipin antibodies (ACAs). Thirteen (35.1%) UEDVT patients were oral contraceptive (OC) users vs. 12 (16%) controls; P = 0.020, OR: 2.89 (95% CI 1.16-7.21). When secondary UEDVT patients were compared with controls, no differences were observed in any of the risk factors analysed. On the other hand, when primary UEDVT was considered, six (12.5%) patients were carriers of the prothrombin G20210A mutation vs. six (3.7%) controls; P = 0.031, OR: 3.76 (95% CI 1.15-12.26). Regarding ACAs, a borderline statistical significance was observed when primary UEDVT was compared with controls, P = 0.048; OR: 4.88 (95% CI 1.05-22.61). In primary UEDVT, 52% of the fertile women were OC users vs. 16% of controls; P = 0.001, OR:5.78 (95% CI 2.13-15.67). When the interaction of both factors, i.e. prothrombin G20210A mutation and OC intake, were considered, the risk increased markedly, indicating a synergistic effect as observed with other thrombotic locations. In patients with primary UEDVT screening for antithrombin, protein C and protein S deficiency and APC resistance would not be justified, although it might be reasonable to determine the carrier status of the prothrombin G20210A mutation only in OC users." @default.
- W133091976 created "2016-06-24" @default.
- W133091976 creator A5021978850 @default.
- W133091976 creator A5026232495 @default.
- W133091976 creator A5029943902 @default.
- W133091976 creator A5038247490 @default.
- W133091976 creator A5039634756 @default.
- W133091976 creator A5041628487 @default.
- W133091976 creator A5057986151 @default.
- W133091976 creator A5068695724 @default.
- W133091976 creator A5087753151 @default.
- W133091976 date "2003-01-01" @default.
- W133091976 modified "2023-10-16" @default.
- W133091976 title "Prothrombin G20210A mutation and oral contraceptive use increase upper-extremity deep vein thrombotic risk" @default.
- W133091976 doi "https://doi.org/10.1055/s-0037-1613373" @default.
- W133091976 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12624627" @default.
- W133091976 hasPublicationYear "2003" @default.
- W133091976 type Work @default.
- W133091976 sameAs 133091976 @default.
- W133091976 citedByCount "44" @default.
- W133091976 countsByYear W1330919762012 @default.
- W133091976 countsByYear W1330919762013 @default.
- W133091976 countsByYear W1330919762014 @default.
- W133091976 countsByYear W1330919762015 @default.
- W133091976 countsByYear W1330919762016 @default.
- W133091976 countsByYear W1330919762017 @default.
- W133091976 countsByYear W1330919762021 @default.
- W133091976 crossrefType "journal-article" @default.
- W133091976 hasAuthorship W133091976A5021978850 @default.
- W133091976 hasAuthorship W133091976A5026232495 @default.
- W133091976 hasAuthorship W133091976A5029943902 @default.
- W133091976 hasAuthorship W133091976A5038247490 @default.
- W133091976 hasAuthorship W133091976A5039634756 @default.
- W133091976 hasAuthorship W133091976A5041628487 @default.
- W133091976 hasAuthorship W133091976A5057986151 @default.
- W133091976 hasAuthorship W133091976A5068695724 @default.
- W133091976 hasAuthorship W133091976A5087753151 @default.
- W133091976 hasConcept C126322002 @default.
- W133091976 hasConcept C146304588 @default.
- W133091976 hasConcept C2777175894 @default.
- W133091976 hasConcept C2777872019 @default.
- W133091976 hasConcept C2778959117 @default.
- W133091976 hasConcept C2780011451 @default.
- W133091976 hasConcept C2780868729 @default.
- W133091976 hasConcept C2780942790 @default.
- W133091976 hasConcept C65409693 @default.
- W133091976 hasConcept C71924100 @default.
- W133091976 hasConcept C90924648 @default.
- W133091976 hasConceptScore W133091976C126322002 @default.
- W133091976 hasConceptScore W133091976C146304588 @default.
- W133091976 hasConceptScore W133091976C2777175894 @default.
- W133091976 hasConceptScore W133091976C2777872019 @default.
- W133091976 hasConceptScore W133091976C2778959117 @default.
- W133091976 hasConceptScore W133091976C2780011451 @default.
- W133091976 hasConceptScore W133091976C2780868729 @default.
- W133091976 hasConceptScore W133091976C2780942790 @default.
- W133091976 hasConceptScore W133091976C65409693 @default.
- W133091976 hasConceptScore W133091976C71924100 @default.
- W133091976 hasConceptScore W133091976C90924648 @default.
- W133091976 hasIssue "03" @default.
- W133091976 hasLocation W1330919761 @default.
- W133091976 hasLocation W1330919762 @default.
- W133091976 hasOpenAccess W133091976 @default.
- W133091976 hasPrimaryLocation W1330919761 @default.
- W133091976 hasRelatedWork W1998982063 @default.
- W133091976 hasRelatedWork W2083381696 @default.
- W133091976 hasRelatedWork W2350491188 @default.
- W133091976 hasRelatedWork W2355627001 @default.
- W133091976 hasRelatedWork W2366675370 @default.
- W133091976 hasRelatedWork W2460356074 @default.
- W133091976 hasRelatedWork W3176315209 @default.
- W133091976 hasRelatedWork W3201903435 @default.
- W133091976 hasRelatedWork W4200039973 @default.
- W133091976 hasRelatedWork W4377094050 @default.
- W133091976 hasVolume "89" @default.
- W133091976 isParatext "false" @default.
- W133091976 isRetracted "false" @default.
- W133091976 magId "133091976" @default.
- W133091976 workType "article" @default.