FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W133282222> ?p ?o ?g. }

• W133282222 endingPage "79" @default.
• W133282222 startingPage "169" @default.
• W133282222 abstract "Placement of extracellular matrix components has been used as a mean to enhance axonal growth across nerve long gaps repaired by tubulization. However, such matrices may impede axonal regeneration depending on its density and microgeometry.Silicone tubes were prefilled with collagen or laminin-containing gels and implanted into a 6 mm gap, a length considered limiting for regeneration, in the mouse sciatic nerve. Gels were polymerized prior to implantation either in horizontal position or subjected to gravitational (in vertical position) or to magnetic forces to induce longitudinal alignment of the fibrils. Recovery of motor, sensory and sudomotor functions in the hindpaw was evaluated during 4 months postoperation.Reinnervation started earlier and achieved slightly higher levels with aligned collagen gels than with the horizontal gel. For the three groups repaired with tubes with Matrigel, there was a gradation of the functional results, reinnervation started earlier and reached higher values in matrix with magnetically-induced, longitudinal orientation than with the horizontal gel, whereas gravitational alignment followed an intermediate evolution. Final morphological evaluation showed more dense residual mass of collagen than of Matrigel at the center of the regenerate nerves. The number of myelinated fibers was increased in tubes with alignment compared to horizontal gels.Alignment of collagen and laminin gels within a silicone tube increases the success and the quality of regeneration in long nerve gaps. The laminin gel performed better than the collagen gel under each condition tested. The combination of an aligned matrix with embedded Schwann cells should be considered in further steps for the development of an artificial nerve graft for clinical application." @default.
• W133282222 created "2016-06-24" @default.
• W133282222 creator A5008739889 @default.
• W133282222 creator A5028187141 @default.
• W133282222 creator A5059691435 @default.
• W133282222 creator A5071004621 @default.
• W133282222 creator A5076449533 @default.
• W133282222 creator A5081147260 @default.
• W133282222 date "2002-01-01" @default.
• W133282222 modified "2023-09-23" @default.
• W133282222 title "Alignment of collagen and laminin-containing gels improve nerve regeneration within silicone tubes." @default.
• W133282222 cites W121816017 @default.
• W133282222 cites W13686736 @default.
• W133282222 cites W13985742 @default.
• W133282222 cites W1485806448 @default.
• W133282222 cites W1662086476 @default.
• W133282222 cites W1821405535 @default.
• W133282222 cites W1964810819 @default.
• W133282222 cites W1968969091 @default.
• W133282222 cites W1969338596 @default.
• W133282222 cites W1971381787 @default.
• W133282222 cites W1973501593 @default.
• W133282222 cites W1974421142 @default.
• W133282222 cites W1975712001 @default.
• W133282222 cites W1979721135 @default.
• W133282222 cites W1983776987 @default.
• W133282222 cites W1984957600 @default.
• W133282222 cites W1986062352 @default.
• W133282222 cites W1996436631 @default.
• W133282222 cites W1997886610 @default.
• W133282222 cites W1998855928 @default.
• W133282222 cites W1998884668 @default.
• W133282222 cites W2006501418 @default.
• W133282222 cites W2013533158 @default.
• W133282222 cites W2014377586 @default.
• W133282222 cites W2018121061 @default.
• W133282222 cites W2020165673 @default.
• W133282222 cites W2031705137 @default.
• W133282222 cites W2034089692 @default.
• W133282222 cites W2037187331 @default.
• W133282222 cites W2041993072 @default.
• W133282222 cites W2042724643 @default.
• W133282222 cites W2045684496 @default.
• W133282222 cites W2048471747 @default.
• W133282222 cites W2054611998 @default.
• W133282222 cites W2055261698 @default.
• W133282222 cites W2063405235 @default.
• W133282222 cites W2074936342 @default.
• W133282222 cites W2077564746 @default.
• W133282222 cites W2082180854 @default.
• W133282222 cites W2091459184 @default.
• W133282222 cites W2094209383 @default.
• W133282222 cites W2101093152 @default.
• W133282222 cites W2110586785 @default.
• W133282222 cites W2121312142 @default.
• W133282222 cites W2134045624 @default.
• W133282222 cites W229272858 @default.
• W133282222 cites W2314594956 @default.
• W133282222 cites W2317975206 @default.
• W133282222 cites W2402540272 @default.
• W133282222 cites W2416060739 @default.
• W133282222 cites W2592300961 @default.
• W133282222 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12515893" @default.
• W133282222 hasPublicationYear "2002" @default.
• W133282222 type Work @default.
• W133282222 sameAs 133282222 @default.
• W133282222 citedByCount "23" @default.
• W133282222 countsByYear W1332822222012 @default.
• W133282222 countsByYear W1332822222014 @default.
• W133282222 countsByYear W1332822222015 @default.
• W133282222 countsByYear W1332822222016 @default.
• W133282222 countsByYear W1332822222017 @default.
• W133282222 countsByYear W1332822222018 @default.
• W133282222 countsByYear W1332822222022 @default.
• W133282222 countsByYear W1332822222023 @default.
• W133282222 crossrefType "journal-article" @default.
• W133282222 hasAuthorship W133282222A5008739889 @default.
• W133282222 hasAuthorship W133282222A5028187141 @default.
• W133282222 hasAuthorship W133282222A5059691435 @default.
• W133282222 hasAuthorship W133282222A5071004621 @default.
• W133282222 hasAuthorship W133282222A5076449533 @default.
• W133282222 hasAuthorship W133282222A5081147260 @default.
• W133282222 hasConcept C105702510 @default.
• W133282222 hasConcept C108586683 @default.
• W133282222 hasConcept C12554922 @default.
• W133282222 hasConcept C136229726 @default.
• W133282222 hasConcept C1491633281 @default.
• W133282222 hasConcept C159985019 @default.
• W133282222 hasConcept C171056886 @default.
• W133282222 hasConcept C185592680 @default.
• W133282222 hasConcept C188027245 @default.
• W133282222 hasConcept C189165786 @default.
• W133282222 hasConcept C192562407 @default.
• W133282222 hasConcept C2778608917 @default.
• W133282222 hasConcept C2779530196 @default.
• W133282222 hasConcept C2779649809 @default.
• W133282222 hasConcept C2779769944 @default.
• W133282222 hasConcept C2779814568 @default.

• next