Matches in SemOpenAlex for { <https://semopenalex.org/work/W133676982> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W133676982 endingPage "28" @default.
- W133676982 startingPage "215" @default.
- W133676982 abstract "Three recent cases from one institution using the total artificial heart (TAH) before transplantation are reviewed. The first patient was implanted for 12 hours with the pneumatic Phoenix total artificial heart after failure of a donor heart 1 day after transplant. Following retransplantation the patient died from severe pulmonary edema, pulmonary hypertension, right ventricular failure, and Pseudomonas septicemia. The second patient was implanted with the Jarvik-7 total artificial heart for rapidly deteriorating idiopathic cardiomyopathy. Major complications during the 9 1/2-day implant consisted of severe pulmonary edema for the first 4 days and a multifocal cerebral embolic event on the seventh day after implantation from which he fully recovered. Major problems after transplant included disseminated toxoplasmosis and two mild episodes of rejection. The patient was discharged 68 days after surgery and remains well. The third patient was a 40-year-old woman with rapidly progressing acute influenza A viral myocarditis. Despite immunosuppressive and antiviral therapy, cardiogenic shock with multiple organ failure developed. The 70 ml Jarvik-7 was implanted for 4 1/2 days. Acute humoral rejection from autoantibodies and alloantibodies led to a cardiac arrest on the second day after transplantation. A second 70 ml Jarvik-7 implant was followed by severe multisystem and infectious complications. After prolonged intensive care support, the patient recovered and is now awaiting transplantation. Nearly 100% cytotoxic antibody reactivity caused by multiple antigenic stimuli is preventing ready access to donor hearts for this patient. We view the current role of the total artificial heart as a tool to preserve life until a suitable donor heart can be found, reverse the end-organ effects of progressive heart failure and low output, and restore transplant candidacy in selected patients with temporary reversible contraindications to transplantation." @default.
- W133676982 created "2016-06-24" @default.
- W133676982 creator A5005524720 @default.
- W133676982 creator A5017047759 @default.
- W133676982 creator A5026380192 @default.
- W133676982 creator A5064402960 @default.
- W133676982 creator A5068678788 @default.
- W133676982 creator A5076208538 @default.
- W133676982 creator A5085085714 @default.
- W133676982 creator A5087095891 @default.
- W133676982 date "1986-05-01" @default.
- W133676982 modified "2023-09-27" @default.
- W133676982 title "Three recent cases of the total artificial heart before transplantation." @default.
- W133676982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3302169" @default.
- W133676982 hasPublicationYear "1986" @default.
- W133676982 type Work @default.
- W133676982 sameAs 133676982 @default.
- W133676982 citedByCount "4" @default.
- W133676982 crossrefType "journal-article" @default.
- W133676982 hasAuthorship W133676982A5005524720 @default.
- W133676982 hasAuthorship W133676982A5017047759 @default.
- W133676982 hasAuthorship W133676982A5026380192 @default.
- W133676982 hasAuthorship W133676982A5064402960 @default.
- W133676982 hasAuthorship W133676982A5068678788 @default.
- W133676982 hasAuthorship W133676982A5076208538 @default.
- W133676982 hasAuthorship W133676982A5085085714 @default.
- W133676982 hasAuthorship W133676982A5087095891 @default.
- W133676982 hasConcept C126322002 @default.
- W133676982 hasConcept C141071460 @default.
- W133676982 hasConcept C164705383 @default.
- W133676982 hasConcept C2776342676 @default.
- W133676982 hasConcept C2776468924 @default.
- W133676982 hasConcept C2776850375 @default.
- W133676982 hasConcept C2777714996 @default.
- W133676982 hasConcept C2778198053 @default.
- W133676982 hasConcept C2778849806 @default.
- W133676982 hasConcept C2780930700 @default.
- W133676982 hasConcept C2781411149 @default.
- W133676982 hasConcept C2911091166 @default.
- W133676982 hasConcept C500558357 @default.
- W133676982 hasConcept C71924100 @default.
- W133676982 hasConceptScore W133676982C126322002 @default.
- W133676982 hasConceptScore W133676982C141071460 @default.
- W133676982 hasConceptScore W133676982C164705383 @default.
- W133676982 hasConceptScore W133676982C2776342676 @default.
- W133676982 hasConceptScore W133676982C2776468924 @default.
- W133676982 hasConceptScore W133676982C2776850375 @default.
- W133676982 hasConceptScore W133676982C2777714996 @default.
- W133676982 hasConceptScore W133676982C2778198053 @default.
- W133676982 hasConceptScore W133676982C2778849806 @default.
- W133676982 hasConceptScore W133676982C2780930700 @default.
- W133676982 hasConceptScore W133676982C2781411149 @default.
- W133676982 hasConceptScore W133676982C2911091166 @default.
- W133676982 hasConceptScore W133676982C500558357 @default.
- W133676982 hasConceptScore W133676982C71924100 @default.
- W133676982 hasIssue "3" @default.
- W133676982 hasLocation W1336769821 @default.
- W133676982 hasOpenAccess W133676982 @default.
- W133676982 hasPrimaryLocation W1336769821 @default.
- W133676982 hasRelatedWork W1970731722 @default.
- W133676982 hasRelatedWork W1996500968 @default.
- W133676982 hasRelatedWork W2048457765 @default.
- W133676982 hasRelatedWork W2203560198 @default.
- W133676982 hasRelatedWork W2207720790 @default.
- W133676982 hasRelatedWork W2401736111 @default.
- W133676982 hasRelatedWork W2408534260 @default.
- W133676982 hasRelatedWork W2412475215 @default.
- W133676982 hasRelatedWork W2478999338 @default.
- W133676982 hasRelatedWork W3143860339 @default.
- W133676982 hasVolume "5" @default.
- W133676982 isParatext "false" @default.
- W133676982 isRetracted "false" @default.
- W133676982 magId "133676982" @default.
- W133676982 workType "article" @default.