Matches in SemOpenAlex for { <https://semopenalex.org/work/W133925742> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W133925742 endingPage "5" @default.
- W133925742 startingPage "450" @default.
- W133925742 abstract "To investigate the immune response of surgical patients to injury and sepsis, we measured total lymphocyte counts and T-cell subsets in five nonseptic and 17 septic subjects. Total lymphocyte and T-cell levels declined to similar degrees following injury or sepsis and did not appear to be of value as prognostic indicators. However, analysis of T-cell subsets in septic patients indicated that survivors exhibited normal T-cell subpopulations as well as helper to suppressor cell ratios. Nonsurvivors generally exhibited a selective depression of helper (OKT4) T-cells and the resultant degree of helper to suppressor ratio decline was directly related to mortality. A helper to suppressor ratio (OKT4/T8) below 0.6 was uniformly associated with a fatal outcome. Finally, a small subgroup of septic nonsurviving patients exhibited a selective depression of suppressor (OKT8) lymphocytes which also appeared to carry an unfavorable prognosis. These data indicate that T-lymphocyte subpopulation analysis is a useful predictor of hospital course." @default.
- W133925742 created "2016-06-24" @default.
- W133925742 creator A5007622439 @default.
- W133925742 creator A5017710651 @default.
- W133925742 creator A5023883325 @default.
- W133925742 creator A5074054484 @default.
- W133925742 date "1988-07-01" @default.
- W133925742 modified "2023-09-23" @default.
- W133925742 title "Altered T-lymphocyte subsets in severe sepsis." @default.
- W133925742 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3260458" @default.
- W133925742 hasPublicationYear "1988" @default.
- W133925742 type Work @default.
- W133925742 sameAs 133925742 @default.
- W133925742 citedByCount "6" @default.
- W133925742 countsByYear W1339257422015 @default.
- W133925742 countsByYear W1339257422017 @default.
- W133925742 countsByYear W1339257422021 @default.
- W133925742 crossrefType "journal-article" @default.
- W133925742 hasAuthorship W133925742A5007622439 @default.
- W133925742 hasAuthorship W133925742A5017710651 @default.
- W133925742 hasAuthorship W133925742A5023883325 @default.
- W133925742 hasAuthorship W133925742A5074054484 @default.
- W133925742 hasConcept C121608353 @default.
- W133925742 hasConcept C126322002 @default.
- W133925742 hasConcept C179185449 @default.
- W133925742 hasConcept C203014093 @default.
- W133925742 hasConcept C2776090121 @default.
- W133925742 hasConcept C2777761686 @default.
- W133925742 hasConcept C2778384902 @default.
- W133925742 hasConcept C2781136212 @default.
- W133925742 hasConcept C2992881475 @default.
- W133925742 hasConcept C3020391436 @default.
- W133925742 hasConcept C71924100 @default.
- W133925742 hasConcept C8891405 @default.
- W133925742 hasConceptScore W133925742C121608353 @default.
- W133925742 hasConceptScore W133925742C126322002 @default.
- W133925742 hasConceptScore W133925742C179185449 @default.
- W133925742 hasConceptScore W133925742C203014093 @default.
- W133925742 hasConceptScore W133925742C2776090121 @default.
- W133925742 hasConceptScore W133925742C2777761686 @default.
- W133925742 hasConceptScore W133925742C2778384902 @default.
- W133925742 hasConceptScore W133925742C2781136212 @default.
- W133925742 hasConceptScore W133925742C2992881475 @default.
- W133925742 hasConceptScore W133925742C3020391436 @default.
- W133925742 hasConceptScore W133925742C71924100 @default.
- W133925742 hasConceptScore W133925742C8891405 @default.
- W133925742 hasIssue "7" @default.
- W133925742 hasLocation W1339257421 @default.
- W133925742 hasOpenAccess W133925742 @default.
- W133925742 hasPrimaryLocation W1339257421 @default.
- W133925742 hasRelatedWork W133925742 @default.
- W133925742 hasRelatedWork W1412788897 @default.
- W133925742 hasRelatedWork W1986051408 @default.
- W133925742 hasRelatedWork W2025398935 @default.
- W133925742 hasRelatedWork W2067477085 @default.
- W133925742 hasRelatedWork W2092781537 @default.
- W133925742 hasRelatedWork W2112862714 @default.
- W133925742 hasRelatedWork W2358129317 @default.
- W133925742 hasRelatedWork W2411971152 @default.
- W133925742 hasRelatedWork W2415801785 @default.
- W133925742 hasVolume "54" @default.
- W133925742 isParatext "false" @default.
- W133925742 isRetracted "false" @default.
- W133925742 magId "133925742" @default.
- W133925742 workType "article" @default.