Matches in SemOpenAlex for { <https://semopenalex.org/work/W133991185> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W133991185 endingPage "259" @default.
- W133991185 startingPage "250" @default.
- W133991185 abstract "14 insulinomas were examined immunohistologically using the peroxidase labelled antibody method. 8 tumours were investigated immediately after extirpation. 7 of these reacted with insulin and porcine-C-peptide antisera but not with glucagon antiserum. Only a B-cell carcinoma with an unusually low insulin concentration was negative. One year after embedding in paraffin the immunohistologic reaction with insulin antiserum had markedly decreased in the tumours; however, not in the islet of the adjacent pancreas. From 6 patients 1 to 4 years old paraffin-embedded material of the tumour and the normal pancreas was available. In this group 4 tumours with an elevated insulin concentration reacted immunohistologically only weakly with an insulin antiserum and two tumours (one with high and one with low insulin concentration were immunohistologically negative, while the islets of the adjacent panceas of all six cases showed a strong reaction. Thus the immunohistilogic reaction of insulin in B-cell tumours but not in normal islets depends on the time elapsed between the paraffin embedding and the examination. Only tumours fixed in Bouin's fluid but not in Karnovsky's solution gave a positive immunohistologie reaction, while the islets of the adjacent pancreas reacted positively also after fixation in Karnovsky's solution. These findings suggest differences between the normal and the tumour insulin. A correlation between aldehyde-thionin stain and immunohistology indicates the superiority of immunohistology in identifying insulin producing tumour cells." @default.
- W133991185 created "2016-06-24" @default.
- W133991185 creator A5005112417 @default.
- W133991185 creator A5006244909 @default.
- W133991185 creator A5047101257 @default.
- W133991185 creator A5084041491 @default.
- W133991185 date "1972-08-01" @default.
- W133991185 modified "2023-09-25" @default.
- W133991185 title "Immunohistologic investigations of human insulinomas" @default.
- W133991185 cites W1970591067 @default.
- W133991185 cites W2006387884 @default.
- W133991185 cites W2009320665 @default.
- W133991185 cites W2012089245 @default.
- W133991185 cites W2012739617 @default.
- W133991185 cites W2022341211 @default.
- W133991185 cites W2022942781 @default.
- W133991185 cites W2028431435 @default.
- W133991185 cites W2029676308 @default.
- W133991185 cites W2059913862 @default.
- W133991185 cites W2062082681 @default.
- W133991185 cites W2078368108 @default.
- W133991185 cites W2078585683 @default.
- W133991185 cites W2111039706 @default.
- W133991185 cites W2153660163 @default.
- W133991185 cites W2312513482 @default.
- W133991185 cites W2316747228 @default.
- W133991185 cites W2429700486 @default.
- W133991185 cites W52403050 @default.
- W133991185 doi "https://doi.org/10.1007/bf01225568" @default.
- W133991185 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4344285" @default.
- W133991185 hasPublicationYear "1972" @default.
- W133991185 type Work @default.
- W133991185 sameAs 133991185 @default.
- W133991185 citedByCount "22" @default.
- W133991185 crossrefType "journal-article" @default.
- W133991185 hasAuthorship W133991185A5005112417 @default.
- W133991185 hasAuthorship W133991185A5006244909 @default.
- W133991185 hasAuthorship W133991185A5047101257 @default.
- W133991185 hasAuthorship W133991185A5084041491 @default.
- W133991185 hasBestOaLocation W1339911851 @default.
- W133991185 hasConcept C126322002 @default.
- W133991185 hasConcept C134018914 @default.
- W133991185 hasConcept C142724271 @default.
- W133991185 hasConcept C159654299 @default.
- W133991185 hasConcept C165220095 @default.
- W133991185 hasConcept C185592680 @default.
- W133991185 hasConcept C203014093 @default.
- W133991185 hasConcept C204232928 @default.
- W133991185 hasConcept C2778563252 @default.
- W133991185 hasConcept C2778764654 @default.
- W133991185 hasConcept C2779306644 @default.
- W133991185 hasConcept C2781294515 @default.
- W133991185 hasConcept C71924100 @default.
- W133991185 hasConcept C74864618 @default.
- W133991185 hasConcept C86803240 @default.
- W133991185 hasConcept C91523082 @default.
- W133991185 hasConceptScore W133991185C126322002 @default.
- W133991185 hasConceptScore W133991185C134018914 @default.
- W133991185 hasConceptScore W133991185C142724271 @default.
- W133991185 hasConceptScore W133991185C159654299 @default.
- W133991185 hasConceptScore W133991185C165220095 @default.
- W133991185 hasConceptScore W133991185C185592680 @default.
- W133991185 hasConceptScore W133991185C203014093 @default.
- W133991185 hasConceptScore W133991185C204232928 @default.
- W133991185 hasConceptScore W133991185C2778563252 @default.
- W133991185 hasConceptScore W133991185C2778764654 @default.
- W133991185 hasConceptScore W133991185C2779306644 @default.
- W133991185 hasConceptScore W133991185C2781294515 @default.
- W133991185 hasConceptScore W133991185C71924100 @default.
- W133991185 hasConceptScore W133991185C74864618 @default.
- W133991185 hasConceptScore W133991185C86803240 @default.
- W133991185 hasConceptScore W133991185C91523082 @default.
- W133991185 hasIssue "4" @default.
- W133991185 hasLocation W1339911851 @default.
- W133991185 hasLocation W1339911852 @default.
- W133991185 hasOpenAccess W133991185 @default.
- W133991185 hasPrimaryLocation W1339911851 @default.
- W133991185 hasRelatedWork W1583213500 @default.
- W133991185 hasRelatedWork W1981564790 @default.
- W133991185 hasRelatedWork W1984592363 @default.
- W133991185 hasRelatedWork W2017797235 @default.
- W133991185 hasRelatedWork W2026121087 @default.
- W133991185 hasRelatedWork W2028699422 @default.
- W133991185 hasRelatedWork W2084878141 @default.
- W133991185 hasRelatedWork W2140621396 @default.
- W133991185 hasRelatedWork W2402098708 @default.
- W133991185 hasRelatedWork W2406617150 @default.
- W133991185 hasVolume "8" @default.
- W133991185 isParatext "false" @default.
- W133991185 isRetracted "false" @default.
- W133991185 magId "133991185" @default.
- W133991185 workType "article" @default.