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- W134690645 abstract "Mammalian central nervous system neurons are characterized by differential responses to incoming stimuli and storage of the information elicited by external stimuli. Calcium (Ca2+) influx through select populations of neurotransmitter-activated receptors, the glutamate receptors, when coupled with the induction of Ca2+ release from intracellular stores, initiates key molecular interactions and enzyme activities that lead to long-term changes in transcription, protein synthesis, and neuronal responses to external stimuli. Glutamate receptor ion channels fall into three main classes based on molecular structure and pharmacological sensitivities. These ligand-activated ion channels are differentially permeable to Ca2+ and their activation can lead to either long-term potentiation or depression of synaptic activity." @default.
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- W134690645 date "2013-01-01" @default.
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- W134690645 title "Ligand-Operated Membrane Channels: Calcium (Glutamate)" @default.
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- W134690645 doi "https://doi.org/10.1016/b978-0-12-378630-2.00288-7" @default.
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