FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W135152783> ?p ?o ?g. }

• W135152783 endingPage "85" @default.
• W135152783 startingPage "76" @default.
• W135152783 abstract "The aim of this study was to investigate the possible effects of antiretroviral therapy (ART) in utero on cardiac development and function in human immunodeficiency virus (HIV)-negative children.ART reduces vertical HIV transmission. Long-term cardiotoxicity after in utero exposure to ART is unknown in children but has occurred in young animals.Using a prospective multisite cohort study design, echocardiograms taken between birth and 24 months were compared in 2 groups of HIV-negative infants of HIV-positive mothers: 136 infants exposed to ART (ART+) and 216 unexposed infants (ART-).Mean left ventricular (LV) mass z-scores were consistently lower in ART+ girls than in ART- girls: differences in mean z-scores were -0.46 at birth (p = 0.005), -1.02 at 6 months (p < 0.001), -0.74 at 12 months (p < 0.001), and -0.79 at 24 months (p < 0.001). Corresponding differences in z-scores for boys were smaller: 0.13 at 1 month (p = 0.42), -0.44 at 6 months (p = 0.01), -0.15 at 12 months (p = 0.37), and -0.21 at 24 months (p = 0.21). Septal wall thickness and LV dimension were smaller than expected in ART+ infants, but LV contractility was consistently about 1 SD higher at all ages (p < 0.001). In ART+ infants, LV fractional shortening was higher than in ART- infants; girls showed a greater difference.Fetal exposure to ART is associated with reduced LV mass, LV dimension, and septal wall thickness z-scores and increased LV fractional shortening and contractility up to age 2 years. These effects are more pronounced in girls than in boys. Fetal ART exposure may impair myocardial growth while improving depressed LV function." @default.
• W135152783 created "2016-06-24" @default.
• W135152783 creator A5000020632 @default.
• W135152783 creator A5006947863 @default.
• W135152783 creator A5007442463 @default.
• W135152783 creator A5008457915 @default.
• W135152783 creator A5016365640 @default.
• W135152783 creator A5023876677 @default.
• W135152783 creator A5024916797 @default.
• W135152783 creator A5033742702 @default.
• W135152783 creator A5041462500 @default.
• W135152783 creator A5046706720 @default.
• W135152783 creator A5066577289 @default.
• W135152783 creator A5082899595 @default.
• W135152783 creator A5083867086 @default.
• W135152783 creator A5084302638 @default.
• W135152783 creator A5084561191 @default.
• W135152783 creator A5089117587 @default.
• W135152783 creator A5028621905 @default.
• W135152783 date "2011-01-01" @default.
• W135152783 modified "2023-10-16" @default.
• W135152783 title "Cardiac Effects of Antiretroviral Therapy in HIV-Negative Infants Born to HIV-Positive Mothers" @default.
• W135152783 cites W1935834387 @default.
• W135152783 cites W1987760157 @default.
• W135152783 cites W1999697653 @default.
• W135152783 cites W2014307930 @default.
• W135152783 cites W2015758016 @default.
• W135152783 cites W2042454140 @default.
• W135152783 cites W2042846521 @default.
• W135152783 cites W2044934343 @default.
• W135152783 cites W2054850913 @default.
• W135152783 cites W2058337944 @default.
• W135152783 cites W2060235433 @default.
• W135152783 cites W2061549298 @default.
• W135152783 cites W2063943955 @default.
• W135152783 cites W2066377662 @default.
• W135152783 cites W2066935730 @default.
• W135152783 cites W2067239496 @default.
• W135152783 cites W2070139934 @default.
• W135152783 cites W2072696546 @default.
• W135152783 cites W2072747307 @default.
• W135152783 cites W2085560533 @default.
• W135152783 cites W2089504584 @default.
• W135152783 cites W2090014878 @default.
• W135152783 cites W2090886995 @default.
• W135152783 cites W2111112758 @default.
• W135152783 cites W2113906937 @default.
• W135152783 cites W2119970311 @default.
• W135152783 cites W2123885366 @default.
• W135152783 cites W2137994859 @default.
• W135152783 cites W2141209516 @default.
• W135152783 cites W2149860264 @default.
• W135152783 cites W2156580873 @default.
• W135152783 cites W2161082810 @default.
• W135152783 cites W2165674876 @default.
• W135152783 cites W2167545532 @default.
• W135152783 cites W2312499014 @default.
• W135152783 cites W2317429974 @default.
• W135152783 cites W2341053160 @default.
• W135152783 cites W2595380319 @default.
• W135152783 cites W2679757027 @default.
• W135152783 cites W3139782874 @default.
• W135152783 cites W4254793567 @default.
• W135152783 cites W4367435830 @default.
• W135152783 cites W48462804 @default.
• W135152783 cites W2029833746 @default.
• W135152783 doi "https://doi.org/10.1016/j.jacc.2010.08.620" @default.
• W135152783 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3243620" @default.
• W135152783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21185505" @default.
• W135152783 hasPublicationYear "2011" @default.
• W135152783 type Work @default.
• W135152783 sameAs 135152783 @default.
• W135152783 citedByCount "74" @default.
• W135152783 countsByYear W1351527832012 @default.
• W135152783 countsByYear W1351527832013 @default.
• W135152783 countsByYear W1351527832014 @default.
• W135152783 countsByYear W1351527832015 @default.
• W135152783 countsByYear W1351527832016 @default.
• W135152783 countsByYear W1351527832017 @default.
• W135152783 countsByYear W1351527832018 @default.
• W135152783 countsByYear W1351527832019 @default.
• W135152783 countsByYear W1351527832020 @default.
• W135152783 countsByYear W1351527832021 @default.
• W135152783 countsByYear W1351527832022 @default.
• W135152783 countsByYear W1351527832023 @default.
• W135152783 crossrefType "journal-article" @default.
• W135152783 hasAuthorship W135152783A5000020632 @default.
• W135152783 hasAuthorship W135152783A5006947863 @default.
• W135152783 hasAuthorship W135152783A5007442463 @default.
• W135152783 hasAuthorship W135152783A5008457915 @default.
• W135152783 hasAuthorship W135152783A5016365640 @default.
• W135152783 hasAuthorship W135152783A5023876677 @default.
• W135152783 hasAuthorship W135152783A5024916797 @default.
• W135152783 hasAuthorship W135152783A5028621905 @default.
• W135152783 hasAuthorship W135152783A5033742702 @default.
• W135152783 hasAuthorship W135152783A5041462500 @default.
• W135152783 hasAuthorship W135152783A5046706720 @default.
• W135152783 hasAuthorship W135152783A5066577289 @default.

• next