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- W135322061 abstract "Cadmium has been implicated in the pathogenesis of human hypertension and arteriosclerotic heart disease. Various experiments showed that cadmium could influence the vasopressor-induced reactivity and the stress-strain characteristics of the blood vessel wall. Smoking is considered to be one of the risk factors in accumulating high amounts of cadmium in human organic tissue. Therefore, in the present study the cadmium content of the blood and the heart tissue was evaluated in smoking and non-smoking patients who suffered from coronary heart diseases and various vascular defects. Blood and heart tissue samples of 49 patients undergoing a heart operation were examined. The measurements were carried out with atomic absorption spectometry. Cadmium concentration in the blood was elevated significantly in smoking patients versus non-smokers. In the heart tissue samples of smoking patients cadmium was increased as well towards non-smoking patients. These data show that smoking influences the cadmium intake and it may support the opinion of different research groups that cadmium might have a toxic effect on the myocardium and that cadmium accumulation is another risk factor in the development of coronary heart disease. 10 references, 1 figure." @default.
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- W135322061 date "1986-01-01" @default.
- W135322061 modified "2023-09-28" @default.
- W135322061 title "Cadmium in the blood and heart tissue of patients (smokers/non-smokers) with coronary heart disease" @default.
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