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- W136115385 abstract "Abstract A new type of kasugamycin-resistant mutant has been isolated from E. coli K12, strain AB312 (Hfr, lac,thr,leu,thi,strA,fus ). In a cell-free protein-synthetic system, the resistance is localized in the ribosome but not in the supernatant fraction. On initiation complex formation, the resistance is associated with the washed ribosome but not with initiation factors. In reconstitution of the 30S ribosomal subunit, the resistance is due to the protein(s) but not to 16S RNA. In two-dimensional electrophoresis, protein S2 is deficient in the 30S ribosomal subunit of kasugamycin-resistant mutant. The results indicate that the kasugamycin-resistance is attributed to alteration of ribosomal protein S2." @default.
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- W136115385 date "1974-10-01" @default.
- W136115385 modified "2023-10-16" @default.
- W136115385 title "Alteration of ribosomal protein S2 in kasugamycin-resistant mutant derived from AB312" @default.
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- W136115385 doi "https://doi.org/10.1016/0006-291x(74)90434-3" @default.
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