Matches in SemOpenAlex for { <https://semopenalex.org/work/W13636749> ?p ?o ?g. }
- W13636749 endingPage "38" @default.
- W13636749 startingPage "129" @default.
- W13636749 abstract "This study investigates if glycyrrhizin, a constituent of licorice (Glycyrrhiza glabra) root, is able to treat the complications (insulin resistance, hyperglycemia, dyslipidemia and oxidative stress) of metabolic syndrome. Metabolic syndrome was induced in rats by feeding a fructose-enriched (60%) diet for six weeks, after which single dose of glycyrrhizin (50 mg/kg body weight) was administered intraperitoneally. Different biochemical parameters from blood were estimated during three weeks after treatment. Then the rats were sacrificed to collect skeletal muscle tissue. Glycyrrhizin reduced the enhanced levels of blood glucose, insulin and lipids in metabolic syndrome group. Increased advanced glycation end products of hemoglobin, glycohemoglobin, hemoglobin-mediated iron release and iron-mediated free radical reactions (arachidonic acid and deoxyribose degradation) in metabolic syndrome were inhibited by glycyrrhizin treatment. Reduced activities of enzymatic antioxidants (superoxide dismutase and catalase) and elevated oxidative stress markers (malonaldehyde, fructosamine, hemoglobin carbonyl content and DNA damage) in metabolic syndrome were reversed to almost normal levels by glycyrrhizin. The decreased levels of peroxisome proliferator activated receptor gamma (PPARgamma) and glucose transporter 4 (GLUT4) proteins in skeletal muscle of metabolic syndrome group were elevated by glycyrrhizin, indicating improved fatty acid oxidation and glucose homeostasis." @default.
- W13636749 created "2016-06-24" @default.
- W13636749 creator A5043522398 @default.
- W13636749 creator A5060509118 @default.
- W13636749 creator A5085361878 @default.
- W13636749 date "2013-02-01" @default.
- W13636749 modified "2023-10-18" @default.
- W13636749 title "Glycyrrhizin ameliorates insulin resistance, hyperglycemia, dyslipidemia and oxidative stress in fructose-induced metabolic syndrome-X in rat model." @default.
- W13636749 cites W1567614586 @default.
- W13636749 cites W1605002548 @default.
- W13636749 cites W1734082729 @default.
- W13636749 cites W1768247331 @default.
- W13636749 cites W1775749144 @default.
- W13636749 cites W1837985597 @default.
- W13636749 cites W1903154371 @default.
- W13636749 cites W1969027523 @default.
- W13636749 cites W1971060217 @default.
- W13636749 cites W1973142161 @default.
- W13636749 cites W1977436184 @default.
- W13636749 cites W1990089345 @default.
- W13636749 cites W1993459861 @default.
- W13636749 cites W1996694657 @default.
- W13636749 cites W1999277384 @default.
- W13636749 cites W2008328905 @default.
- W13636749 cites W2025795822 @default.
- W13636749 cites W2028886298 @default.
- W13636749 cites W2030276002 @default.
- W13636749 cites W2035442334 @default.
- W13636749 cites W2046966664 @default.
- W13636749 cites W2048569851 @default.
- W13636749 cites W2057846722 @default.
- W13636749 cites W2060010080 @default.
- W13636749 cites W2061575441 @default.
- W13636749 cites W2061885883 @default.
- W13636749 cites W2071888073 @default.
- W13636749 cites W2075852475 @default.
- W13636749 cites W2078386719 @default.
- W13636749 cites W2088866343 @default.
- W13636749 cites W2092629964 @default.
- W13636749 cites W2098947106 @default.
- W13636749 cites W2113432742 @default.
- W13636749 cites W2116404316 @default.
- W13636749 cites W2118935550 @default.
- W13636749 cites W2153769752 @default.
- W13636749 cites W2160234571 @default.
- W13636749 cites W2253257662 @default.
- W13636749 cites W2263023695 @default.
- W13636749 cites W2300575681 @default.
- W13636749 cites W2419513718 @default.
- W13636749 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23923606" @default.
- W13636749 hasPublicationYear "2013" @default.
- W13636749 type Work @default.
- W13636749 sameAs 13636749 @default.
- W13636749 citedByCount "21" @default.
- W13636749 countsByYear W136367492013 @default.
- W13636749 countsByYear W136367492014 @default.
- W13636749 countsByYear W136367492015 @default.
- W13636749 countsByYear W136367492016 @default.
- W13636749 countsByYear W136367492017 @default.
- W13636749 countsByYear W136367492018 @default.
- W13636749 countsByYear W136367492019 @default.
- W13636749 countsByYear W136367492020 @default.
- W13636749 countsByYear W136367492022 @default.
- W13636749 countsByYear W136367492023 @default.
- W13636749 crossrefType "journal-article" @default.
- W13636749 hasAuthorship W13636749A5043522398 @default.
- W13636749 hasAuthorship W13636749A5060509118 @default.
- W13636749 hasAuthorship W13636749A5085361878 @default.
- W13636749 hasConcept C126322002 @default.
- W13636749 hasConcept C134018914 @default.
- W13636749 hasConcept C185592680 @default.
- W13636749 hasConcept C2776151105 @default.
- W13636749 hasConcept C2776188179 @default.
- W13636749 hasConcept C2776332754 @default.
- W13636749 hasConcept C2777391703 @default.
- W13636749 hasConcept C2779306644 @default.
- W13636749 hasConcept C2780578515 @default.
- W13636749 hasConcept C555293320 @default.
- W13636749 hasConcept C71924100 @default.
- W13636749 hasConceptScore W13636749C126322002 @default.
- W13636749 hasConceptScore W13636749C134018914 @default.
- W13636749 hasConceptScore W13636749C185592680 @default.
- W13636749 hasConceptScore W13636749C2776151105 @default.
- W13636749 hasConceptScore W13636749C2776188179 @default.
- W13636749 hasConceptScore W13636749C2776332754 @default.
- W13636749 hasConceptScore W13636749C2777391703 @default.
- W13636749 hasConceptScore W13636749C2779306644 @default.
- W13636749 hasConceptScore W13636749C2780578515 @default.
- W13636749 hasConceptScore W13636749C555293320 @default.
- W13636749 hasConceptScore W13636749C71924100 @default.
- W13636749 hasIssue "2" @default.
- W13636749 hasLocation W136367491 @default.
- W13636749 hasOpenAccess W13636749 @default.
- W13636749 hasPrimaryLocation W136367491 @default.
- W13636749 hasRelatedWork W1969567160 @default.
- W13636749 hasRelatedWork W1989708292 @default.
- W13636749 hasRelatedWork W2086520675 @default.
- W13636749 hasRelatedWork W2095154144 @default.