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- W136497350 abstract "This chapter discusses a study to analyze the regulation of amniotic fluid composition in sheep. In 17 pregnant sheep, with chronic in-dwelling catheters in the fetal carotid artery, jugular vein, bladder, and amniotic sac, 40 experiments were performed in which the volume of amniotic fluid was measured by the dilution of injected 125 I-gamma-globulin and 20–30% of the measured volume removed. The amniotic fluid removed was immediately replaced with the isotonic solutions of sodium chloride (0.15 M NaCl), glucose (50 g/1 water), or mannitol (50 g/1 in water). The time courses of return to normal of amniotic fluid concentrations of sodium (Na + ), potassium (K + ), chloride (Cl − ), urea, and creatinine were then determined as well as any accompanying volume changes. The changes that occurred in Na + , K + , and Cl − concentrations when 20–30% amniotic fluid volume was replaced with isotonic mannitol solution. It was seen that all values were back to pre-experimental values by 6 h. The results obtained when isotonic NaCl was the replacement fluid gave the same results." @default.
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- W136497350 date "1981-01-01" @default.
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- W136497350 title "REGULATION OF AMNIOTIC FLUID COMPOSITION IN SHEEP" @default.
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- W136497350 doi "https://doi.org/10.1016/b978-0-08-027341-9.50014-1" @default.
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