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- W136701655 abstract "Prolactinoma, an adenoma, is the most common hormone-secreting pituitary tumor. Pituitary tumors arise from the functioning or hormone-producing cells as well as stromal cells. The prevalence of prolactinoma in the general population is unknown. However, autopsy results demonstrate that 23–27% of individuals have pituitary microadenomas without prior clinical evidence, and 40% of these stain positive for prolactin by immunocytochemical analysis (1,2). Adenomas are frequently classified according to their size, with microadenomas being less than 10 mm in diameter and larger lesions labeled macroadenomas. Most prolactinomas are microadenomas and enlarge (if at all) extremely slowly over time. The risk of progression of untreated microadenomas to macroadenomas is approximately 7%, based on several longitudinal series of patients followed over long periods (3–8). The pathogenesis of prolactinomas is unknown. Clonal analysis of tumor DNA indicates a monoclonal origin and thus a de novo formation (9,10)." @default.
- W136701655 created "2016-06-24" @default.
- W136701655 creator A5044035078 @default.
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- W136701655 date "2003-01-01" @default.
- W136701655 modified "2023-09-23" @default.
- W136701655 title "Pituitary Tumors Other Than Acromegaly" @default.
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- W136701655 doi "https://doi.org/10.1007/978-1-59259-378-1_11" @default.
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