Matches in SemOpenAlex for { <https://semopenalex.org/work/W13712492> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W13712492 endingPage "8" @default.
- W13712492 startingPage "275" @default.
- W13712492 abstract "To report the experience of a single institution in the south of Israel with doxorubicin and ifosfamide-mesna in patients with advanced/recurrent uterine sarcomas.The hospital records of five patients with advanced/recurrent uterine sarcomas who had combination chemotherapy with doxorubicin and ifosfamide-mesna were retrospectively reviewed. Doxorubicin 30 mg/m2 was given on days 1 and 2 and ifosfamide 2000 mg/m2 (+ mesna, W/W 60%) was given on days 1, 2 and 3 of every 21 days. Dose intensity, relative dose intensity and average relative dose intensity (ARDI) of chemotherapy were calculated. Response was determined using clinical evaluation and radiological reports. Toxicity was graded using the National Cancer Institute (NCI) criteria.The median ARDI of the combination of doxorubicin and ifosfamide received by the patients was 0.68 (range, 0.53-0.74). One (20%) patient had disease complete response lasting three months and four (80%) patients had progressive disease. Toxicity was mainly hematological with grade 3 or 4 leukopenia--four (80%) patients, neutropenia--four (80%), thrombocytopenia--one (20%) and anemia--one (20%). Non-hematological toxicity was negligible. At follow-up, four (80%) patients had died of disease and one (20%) was alive with disease.Although the combination of doxorubicin and ifosfamide has certain activity in advanced/recurrent uterine sarcomas, the toxicity is of much concern and the results of treatment in terms of response duration and survival are poor." @default.
- W13712492 created "2016-06-24" @default.
- W13712492 creator A5022792469 @default.
- W13712492 creator A5025229424 @default.
- W13712492 date "2005-01-01" @default.
- W13712492 modified "2023-09-26" @default.
- W13712492 title "Doxorubicin and ifosfamide-mesna in advanced and recurrent uterine sarcomas." @default.
- W13712492 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15991525" @default.
- W13712492 hasPublicationYear "2005" @default.
- W13712492 type Work @default.
- W13712492 sameAs 13712492 @default.
- W13712492 citedByCount "4" @default.
- W13712492 countsByYear W137124922012 @default.
- W13712492 countsByYear W137124922013 @default.
- W13712492 crossrefType "journal-article" @default.
- W13712492 hasAuthorship W13712492A5022792469 @default.
- W13712492 hasAuthorship W13712492A5025229424 @default.
- W13712492 hasConcept C126322002 @default.
- W13712492 hasConcept C126894567 @default.
- W13712492 hasConcept C141071460 @default.
- W13712492 hasConcept C142724271 @default.
- W13712492 hasConcept C143998085 @default.
- W13712492 hasConcept C2776694085 @default.
- W13712492 hasConcept C2776755627 @default.
- W13712492 hasConcept C2777063308 @default.
- W13712492 hasConcept C2777506904 @default.
- W13712492 hasConcept C2778239845 @default.
- W13712492 hasConcept C2778256501 @default.
- W13712492 hasConcept C2780376820 @default.
- W13712492 hasConcept C2780873365 @default.
- W13712492 hasConcept C2781303535 @default.
- W13712492 hasConcept C71924100 @default.
- W13712492 hasConcept C90924648 @default.
- W13712492 hasConceptScore W13712492C126322002 @default.
- W13712492 hasConceptScore W13712492C126894567 @default.
- W13712492 hasConceptScore W13712492C141071460 @default.
- W13712492 hasConceptScore W13712492C142724271 @default.
- W13712492 hasConceptScore W13712492C143998085 @default.
- W13712492 hasConceptScore W13712492C2776694085 @default.
- W13712492 hasConceptScore W13712492C2776755627 @default.
- W13712492 hasConceptScore W13712492C2777063308 @default.
- W13712492 hasConceptScore W13712492C2777506904 @default.
- W13712492 hasConceptScore W13712492C2778239845 @default.
- W13712492 hasConceptScore W13712492C2778256501 @default.
- W13712492 hasConceptScore W13712492C2780376820 @default.
- W13712492 hasConceptScore W13712492C2780873365 @default.
- W13712492 hasConceptScore W13712492C2781303535 @default.
- W13712492 hasConceptScore W13712492C71924100 @default.
- W13712492 hasConceptScore W13712492C90924648 @default.
- W13712492 hasIssue "3" @default.
- W13712492 hasLocation W137124921 @default.
- W13712492 hasOpenAccess W13712492 @default.
- W13712492 hasPrimaryLocation W137124921 @default.
- W13712492 hasRelatedWork W13712492 @default.
- W13712492 hasRelatedWork W1531247282 @default.
- W13712492 hasRelatedWork W1975069591 @default.
- W13712492 hasRelatedWork W2019342836 @default.
- W13712492 hasRelatedWork W2041896056 @default.
- W13712492 hasRelatedWork W2064585990 @default.
- W13712492 hasRelatedWork W2125681121 @default.
- W13712492 hasRelatedWork W2402032689 @default.
- W13712492 hasRelatedWork W2481186346 @default.
- W13712492 hasRelatedWork W4241272925 @default.
- W13712492 hasVolume "26" @default.
- W13712492 isParatext "false" @default.
- W13712492 isRetracted "false" @default.
- W13712492 magId "13712492" @default.
- W13712492 workType "article" @default.