Matches in SemOpenAlex for { <https://semopenalex.org/work/W13717313> ?p ?o ?g. }
- W13717313 endingPage "171" @default.
- W13717313 startingPage "171" @default.
- W13717313 abstract "Due to blood transfusions, thalassemics are often infected with either hepatitis C virus (HCV) or hepatitis B virus and often have hemochromatosis. Hepatocellular carcinoma (HCC) has emerged in thalassemics only recently as a result of the improvement in thalassemia outcomes. In fact, a prospective study estimated an HCC incidence in β-thalassemia of about 2%. Although data are scanty, HCC screening in thalassemics with risk factors for HCC should be carried out. HCV treatments have some efficacy in HCV infected thalassemics despite partial contraindication to ribavirin and iron overload. However, there are no data on how HCV treatment translates into HCC prevention. Preliminary data suggest that HCC treatment in thalassemics should generally have the same outcomes as in non-thalassemics. Although coexistence of severe comorbidities makes liver transplantation challenging, this therapeutic possibility should not be precluded for well selected HCC β-thalassemia patients. In fact, 2 transfusion dependent adult HCC β-thalassemia patients have recently undergone successful liver transplantation with a good outcome. In conclusion, HCC seems to be a developing issue in thalassemia and HCC screening should be carried out. HCC treatment, including liver transplantation, can be performed in selected patients. A multidisciplinary effort is needed for management." @default.
- W13717313 created "2016-06-24" @default.
- W13717313 creator A5068321284 @default.
- W13717313 date "2010-01-01" @default.
- W13717313 modified "2023-10-18" @default.
- W13717313 title "Hepatocellular carcinoma in thalassemia: A critical review" @default.
- W13717313 cites W1480959071 @default.
- W13717313 cites W1828598670 @default.
- W13717313 cites W1980989145 @default.
- W13717313 cites W1997060903 @default.
- W13717313 cites W2000456361 @default.
- W13717313 cites W2000650260 @default.
- W13717313 cites W2006239244 @default.
- W13717313 cites W2006758305 @default.
- W13717313 cites W2007624559 @default.
- W13717313 cites W2009378591 @default.
- W13717313 cites W2020215421 @default.
- W13717313 cites W2037645162 @default.
- W13717313 cites W2038449539 @default.
- W13717313 cites W2053238051 @default.
- W13717313 cites W2053526872 @default.
- W13717313 cites W2059892936 @default.
- W13717313 cites W2064251865 @default.
- W13717313 cites W2074918898 @default.
- W13717313 cites W2076748772 @default.
- W13717313 cites W2088277031 @default.
- W13717313 cites W2096629515 @default.
- W13717313 cites W2105168162 @default.
- W13717313 cites W2116523495 @default.
- W13717313 cites W2131212067 @default.
- W13717313 cites W2132101256 @default.
- W13717313 cites W2150775371 @default.
- W13717313 cites W2163486683 @default.
- W13717313 cites W2165680505 @default.
- W13717313 cites W4243625103 @default.
- W13717313 cites W4244128297 @default.
- W13717313 doi "https://doi.org/10.4254/wjh.v2.i5.171" @default.
- W13717313 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2999281" @default.
- W13717313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21160991" @default.
- W13717313 hasPublicationYear "2010" @default.
- W13717313 type Work @default.
- W13717313 sameAs 13717313 @default.
- W13717313 citedByCount "50" @default.
- W13717313 countsByYear W137173132012 @default.
- W13717313 countsByYear W137173132013 @default.
- W13717313 countsByYear W137173132014 @default.
- W13717313 countsByYear W137173132015 @default.
- W13717313 countsByYear W137173132016 @default.
- W13717313 countsByYear W137173132017 @default.
- W13717313 countsByYear W137173132018 @default.
- W13717313 countsByYear W137173132019 @default.
- W13717313 countsByYear W137173132020 @default.
- W13717313 countsByYear W137173132021 @default.
- W13717313 countsByYear W137173132022 @default.
- W13717313 countsByYear W137173132023 @default.
- W13717313 crossrefType "journal-article" @default.
- W13717313 hasAuthorship W13717313A5068321284 @default.
- W13717313 hasBestOaLocation W137173131 @default.
- W13717313 hasConcept C126322002 @default.
- W13717313 hasConcept C203014093 @default.
- W13717313 hasConcept C2522874641 @default.
- W13717313 hasConcept C2776408679 @default.
- W13717313 hasConcept C2776455275 @default.
- W13717313 hasConcept C2777799968 @default.
- W13717313 hasConcept C2778019345 @default.
- W13717313 hasConcept C2779609443 @default.
- W13717313 hasConcept C2780014101 @default.
- W13717313 hasConcept C2911091166 @default.
- W13717313 hasConcept C71924100 @default.
- W13717313 hasConcept C90924648 @default.
- W13717313 hasConceptScore W13717313C126322002 @default.
- W13717313 hasConceptScore W13717313C203014093 @default.
- W13717313 hasConceptScore W13717313C2522874641 @default.
- W13717313 hasConceptScore W13717313C2776408679 @default.
- W13717313 hasConceptScore W13717313C2776455275 @default.
- W13717313 hasConceptScore W13717313C2777799968 @default.
- W13717313 hasConceptScore W13717313C2778019345 @default.
- W13717313 hasConceptScore W13717313C2779609443 @default.
- W13717313 hasConceptScore W13717313C2780014101 @default.
- W13717313 hasConceptScore W13717313C2911091166 @default.
- W13717313 hasConceptScore W13717313C71924100 @default.
- W13717313 hasConceptScore W13717313C90924648 @default.
- W13717313 hasIssue "5" @default.
- W13717313 hasLocation W137173131 @default.
- W13717313 hasLocation W137173132 @default.
- W13717313 hasLocation W137173133 @default.
- W13717313 hasLocation W137173134 @default.
- W13717313 hasOpenAccess W13717313 @default.
- W13717313 hasPrimaryLocation W137173131 @default.
- W13717313 hasRelatedWork W1558855435 @default.
- W13717313 hasRelatedWork W2008626862 @default.
- W13717313 hasRelatedWork W2055402791 @default.
- W13717313 hasRelatedWork W2139190582 @default.
- W13717313 hasRelatedWork W2193688418 @default.
- W13717313 hasRelatedWork W2297743715 @default.
- W13717313 hasRelatedWork W2755331962 @default.
- W13717313 hasRelatedWork W3141781145 @default.
- W13717313 hasRelatedWork W4225700053 @default.