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- W137182578 abstract "Cyclopropenoid fatty acids (CPFA) have been shown to induce a variety of physiological disorders when fed to animals * Among these are reduced growth, abnormalities in the reproductive process and alterations of lipid metabolism. This study attempted to measure the oxygen consumptions of the liver mitochondria with the substrates of cyclopropenoid fatty acid and . oleic acid during beta-oxidation. The difference in oxygen consumption may give a crude idea about the difference in metabolic rate between cyclopropenoid and mono-unsaturated fatty acid. In this study, female albino rats of Sprague-Dawley strain were divided into two groups, one group was fed four per cent safflower oil as the sole source of fat in the diet, the other group was fed one per cent safflower oil and three per cent Sterculia foetida oil. Fresh rat liver mitochondria preparations were used as the -4 ' enzyme source. The 4x10 M concentrations of oleic acid or methyl sterculate were as substrates. In the media containing liver mitochondria from the safflower oil fed rats, oxygen consumption was two to two and one half times higher with substrate of methyl sterculate than with oleic acid. The same results was observed when the liver mitochondria of CPFA fed rats were used in the incubation media. The incubation media analyzed at 0, 20, 40, and 80 minutes showed a ratio of stearic acid to oleic acid which was higher for the CPFA fed rats than in those fed safflower oil using the same substrate; also, this ratio was found to be higher when methyl sterculate was used as the substrate than when oleic acid was used." @default.
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- W137182578 date "1970-01-01" @default.
- W137182578 modified "2023-09-25" @default.
- W137182578 title "Respiration of cyclopropenoid fatty acids in vitro" @default.
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