Matches in SemOpenAlex for { <https://semopenalex.org/work/W137214826> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W137214826 endingPage "21" @default.
- W137214826 startingPage "3215" @default.
- W137214826 abstract "Previous studies reported interleukin-27 (IL-27), interferon-γ (IFN-γ), or adenosine deaminase (ADA) alone plays a helpful role in diagnosing tuberculous pleural effusion (TPE). The present study aims at comparing the diagnostic accuracy of pleural IL-27, IFN-γ, and ADA, and investigate the diagnostic accuracy of the combination of IL-27, IFN-γ, or/and ADA for differentiating TPE from pleural effusions with the other etiologies.The concentrations of IL-27, IFN-γ and ADA were simultaneously determined in pleural fluids and sera from 40 patients with TPE; 26 with malignant pleural effusion, seven with infectious pleural effusion, and eight with transudative pleural effusion by enzyme linked immunosorbent assay and colorimetric method. The corresponding biochemical indexs were also simultaneously determined.The concentrations of pleural IL-27 and IFN-γ in the tuberculous group were significantly higher than those in the malignant, infectious, and transudative groups. The concentrations of ADA in TPE were significantly higher than those in MPE or transudative effusions, while much lower than those in infectious effusions. Among these three biomarkers, IL-27 was the most effective for TPE diagnosis, with the cut off value of 900.8 ng/L. IL-27 had a high sensitivity of 95% and specificity of 97.6% for differential diagnosis of TPE from non-TPEs. Combinations of IL-27, IFN-γ and ADA measurements further increased the sensitivity or specificity up to 100%.Compared to non-TPEs, IL-27, IFN-γ and ADA all simultaneously increased in TPE; and among these three rapid detection methods, IL-27 appeared to be the best for distinguishing tuberculous from non-TPEs, especially from MPE. Combinations of the three markers (IL-27, IFN-γ and ADA) yielded the highest sensitivity and specificity. These findings suggest that the applications of a new biomarker, IL-27, alone or with IFN-γ and ADA, may contribute to more efficient diagnosis strategies in the management of tuberculous pleurisy." @default.
- W137214826 created "2016-06-24" @default.
- W137214826 creator A5008558592 @default.
- W137214826 creator A5033009742 @default.
- W137214826 creator A5047389443 @default.
- W137214826 creator A5069580658 @default.
- W137214826 creator A5083651118 @default.
- W137214826 creator A5085349179 @default.
- W137214826 date "2013-01-01" @default.
- W137214826 modified "2023-09-24" @default.
- W137214826 title "Combined detections of interleukin 27, interferon-γ, and adenosine deaminase in pleural effusion for diagnosis of tuberculous pleurisy." @default.
- W137214826 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24033939" @default.
- W137214826 hasPublicationYear "2013" @default.
- W137214826 type Work @default.
- W137214826 sameAs 137214826 @default.
- W137214826 citedByCount "22" @default.
- W137214826 countsByYear W1372148262014 @default.
- W137214826 countsByYear W1372148262015 @default.
- W137214826 countsByYear W1372148262016 @default.
- W137214826 countsByYear W1372148262017 @default.
- W137214826 countsByYear W1372148262019 @default.
- W137214826 countsByYear W1372148262020 @default.
- W137214826 countsByYear W1372148262021 @default.
- W137214826 countsByYear W1372148262022 @default.
- W137214826 countsByYear W1372148262023 @default.
- W137214826 crossrefType "journal-article" @default.
- W137214826 hasAuthorship W137214826A5008558592 @default.
- W137214826 hasAuthorship W137214826A5033009742 @default.
- W137214826 hasAuthorship W137214826A5047389443 @default.
- W137214826 hasAuthorship W137214826A5069580658 @default.
- W137214826 hasAuthorship W137214826A5083651118 @default.
- W137214826 hasAuthorship W137214826A5085349179 @default.
- W137214826 hasConcept C126322002 @default.
- W137214826 hasConcept C142724271 @default.
- W137214826 hasConcept C203014093 @default.
- W137214826 hasConcept C2776232967 @default.
- W137214826 hasConcept C2776991684 @default.
- W137214826 hasConcept C2778690821 @default.
- W137214826 hasConcept C2778978224 @default.
- W137214826 hasConcept C2779634585 @default.
- W137214826 hasConcept C2780801072 @default.
- W137214826 hasConcept C2780841837 @default.
- W137214826 hasConcept C2781069245 @default.
- W137214826 hasConcept C3020380090 @default.
- W137214826 hasConcept C34628245 @default.
- W137214826 hasConcept C71924100 @default.
- W137214826 hasConcept C90924648 @default.
- W137214826 hasConceptScore W137214826C126322002 @default.
- W137214826 hasConceptScore W137214826C142724271 @default.
- W137214826 hasConceptScore W137214826C203014093 @default.
- W137214826 hasConceptScore W137214826C2776232967 @default.
- W137214826 hasConceptScore W137214826C2776991684 @default.
- W137214826 hasConceptScore W137214826C2778690821 @default.
- W137214826 hasConceptScore W137214826C2778978224 @default.
- W137214826 hasConceptScore W137214826C2779634585 @default.
- W137214826 hasConceptScore W137214826C2780801072 @default.
- W137214826 hasConceptScore W137214826C2780841837 @default.
- W137214826 hasConceptScore W137214826C2781069245 @default.
- W137214826 hasConceptScore W137214826C3020380090 @default.
- W137214826 hasConceptScore W137214826C34628245 @default.
- W137214826 hasConceptScore W137214826C71924100 @default.
- W137214826 hasConceptScore W137214826C90924648 @default.
- W137214826 hasIssue "17" @default.
- W137214826 hasLocation W1372148261 @default.
- W137214826 hasOpenAccess W137214826 @default.
- W137214826 hasPrimaryLocation W1372148261 @default.
- W137214826 hasRelatedWork W137214826 @default.
- W137214826 hasRelatedWork W2029174447 @default.
- W137214826 hasRelatedWork W2350131787 @default.
- W137214826 hasRelatedWork W2351570768 @default.
- W137214826 hasRelatedWork W2356534733 @default.
- W137214826 hasRelatedWork W2364352870 @default.
- W137214826 hasRelatedWork W2374309072 @default.
- W137214826 hasRelatedWork W2531372645 @default.
- W137214826 hasRelatedWork W2587453458 @default.
- W137214826 hasRelatedWork W3029830909 @default.
- W137214826 hasVolume "126" @default.
- W137214826 isParatext "false" @default.
- W137214826 isRetracted "false" @default.
- W137214826 magId "137214826" @default.
- W137214826 workType "article" @default.