Matches in SemOpenAlex for { <https://semopenalex.org/work/W137243101> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W137243101 endingPage "81.19" @default.
- W137243101 startingPage "81.19" @default.
- W137243101 abstract "Abstract Rabbits are a valuable resource for diagnostic and therapeutic antibodies, are becoming increasingly important for vaccine development and as animal models of human diseases. They remain a major source of polyclonal and monoclonal antibodies because unique characteristics of their immune system result in antibodies of high affinity and specificity. The whole genome shotgun (2x WGS) unfinished Oryctolagus cuniculus database had serious gaps, but assemblies of the 2x WGS sequence were useful for designing primers for PCR by predicting mRNA sequences and exon boundaries. Deeper 7x WGS coverage was completed in 2008 and assembly of a high quality draft rabbit genome sequence is nearing completion. The Thorbecke Inbred Rabbit chosen for sequencing at Broad Institute was less heterozygous than outbred NZW but the Trace Archive of Oryctolagus cuniculus (WGS) reveals heterozygosity at the immunoglobulin heavy chain locus. The ENCODE Project with ~ 1% of rabbit genomic sequence from a different animal has rabbit genes of immunological interest including a gene cluster syntenic with human and mouse containing IL13, IL3, IL4, IL5 and IRF1. Rabbit genome sequences can contribute comparative genomic data, reveal variants of genes of immunological interest, and genetic contributions to animal and human disease susceptibilities. This research was supported by the Intramural Research Program of the NIH, NIAID." @default.
- W137243101 created "2016-06-24" @default.
- W137243101 creator A5044275994 @default.
- W137243101 date "2009-04-01" @default.
- W137243101 modified "2023-10-14" @default.
- W137243101 title "Genes encoding proteins of immunological interest in the Oryctolagus cuniculus (rabbit) whole genome sequences and ENCODE (81.19)" @default.
- W137243101 doi "https://doi.org/10.4049/jimmunol.182.supp.81.19" @default.
- W137243101 hasPublicationYear "2009" @default.
- W137243101 type Work @default.
- W137243101 sameAs 137243101 @default.
- W137243101 citedByCount "0" @default.
- W137243101 crossrefType "journal-article" @default.
- W137243101 hasAuthorship W137243101A5044275994 @default.
- W137243101 hasConcept C101985253 @default.
- W137243101 hasConcept C104317684 @default.
- W137243101 hasConcept C141231307 @default.
- W137243101 hasConcept C150194340 @default.
- W137243101 hasConcept C159654299 @default.
- W137243101 hasConcept C162317418 @default.
- W137243101 hasConcept C18949551 @default.
- W137243101 hasConcept C197077220 @default.
- W137243101 hasConcept C24432333 @default.
- W137243101 hasConcept C53702515 @default.
- W137243101 hasConcept C54355233 @default.
- W137243101 hasConcept C66746571 @default.
- W137243101 hasConcept C70721500 @default.
- W137243101 hasConcept C86803240 @default.
- W137243101 hasConcept C956191 @default.
- W137243101 hasConceptScore W137243101C101985253 @default.
- W137243101 hasConceptScore W137243101C104317684 @default.
- W137243101 hasConceptScore W137243101C141231307 @default.
- W137243101 hasConceptScore W137243101C150194340 @default.
- W137243101 hasConceptScore W137243101C159654299 @default.
- W137243101 hasConceptScore W137243101C162317418 @default.
- W137243101 hasConceptScore W137243101C18949551 @default.
- W137243101 hasConceptScore W137243101C197077220 @default.
- W137243101 hasConceptScore W137243101C24432333 @default.
- W137243101 hasConceptScore W137243101C53702515 @default.
- W137243101 hasConceptScore W137243101C54355233 @default.
- W137243101 hasConceptScore W137243101C66746571 @default.
- W137243101 hasConceptScore W137243101C70721500 @default.
- W137243101 hasConceptScore W137243101C86803240 @default.
- W137243101 hasConceptScore W137243101C956191 @default.
- W137243101 hasIssue "1_Supplement" @default.
- W137243101 hasLocation W1372431011 @default.
- W137243101 hasOpenAccess W137243101 @default.
- W137243101 hasPrimaryLocation W1372431011 @default.
- W137243101 hasRelatedWork W2004669471 @default.
- W137243101 hasRelatedWork W2108497208 @default.
- W137243101 hasRelatedWork W2133403068 @default.
- W137243101 hasRelatedWork W2160649592 @default.
- W137243101 hasRelatedWork W2897728111 @default.
- W137243101 hasRelatedWork W2903885984 @default.
- W137243101 hasRelatedWork W2956596417 @default.
- W137243101 hasRelatedWork W3083802161 @default.
- W137243101 hasRelatedWork W4205667113 @default.
- W137243101 hasRelatedWork W4235874578 @default.
- W137243101 hasVolume "182" @default.
- W137243101 isParatext "false" @default.
- W137243101 isRetracted "false" @default.
- W137243101 magId "137243101" @default.
- W137243101 workType "article" @default.