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- W137263700 abstract "The human mammary gland has at times been considered a relatively dispensable organ relative to survival, regarded as necessary, if at all, only during a period of lactation. Despite this, a long history of scientific interest is associated with this organ because of its seminal role in infant nutrition and well being, and because it is often afflicted by cancer development. It was an interest in cancer and cancer development in the breast that brought about the first series of experiments that led to the current concept of tissue-specific mammary epithelial stem cells. A different approach to understanding mammary epithelial cell lineage was applied by using cell surface markers to distinguish basal (myoepithelial) from luminal (secretory) epithelial cells. In addition to pairs, other informative images would be of juxtaposed cells that were morphologically intermediate between a primitive and differentiated morphology based on the number, type, and development of cytoplasmic organelles. These features are characteristically well developed in the luminal cells of active lactating mammary gland." @default.
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- W137263700 date "2004-01-01" @default.
- W137263700 modified "2023-09-23" @default.
- W137263700 title "Stem Cells in Mammary Epithelium" @default.
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