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- W137279153 abstract "Publisher Summary Acute aseptic meningitis (AM) is mostly a self-limiting, self-healing disease of acute onset and short duration, characterized by an immune response within the central nervous system (CNS) cerebrospinal fluid (CSF) compartment, which is reflected by abnormalities in humoral as well as cell-mediated immune variables in the CSF. This chapter explains the spread of virus in the CNS and discusses experiments conducted over the last few years regarding the humoral and cell-mediated immune responses in AM. Host-dependent factors, including sensitized lymphocytes and antiviral antibodies, are responsible for inhibition of viral spread and elimination of the infection. Abnormalities occurring in the form of increased immunoglobulin concentrations and oligoclonal bands are observed. Careful dissection of the humoral and cell-mediated immune reactions within the CNS as reflected in CSF, compared to peripheral blood, in patients with AM, provides fundamental information about the localized immune response in the CNS–CSF, improving the ability to interpret and utilize new data about immune reactions." @default.
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- W137279153 date "1983-01-01" @default.
- W137279153 modified "2023-10-18" @default.
- W137279153 title "Humoral and Cellular Immunity in Patients with Acute Aseptic Meningitis" @default.
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- W137279153 doi "https://doi.org/10.1016/s0079-6123(08)63849-2" @default.
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