Matches in SemOpenAlex for { <https://semopenalex.org/work/W137282726> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W137282726 abstract "Excitation-contraction coupling (ECC) and cardiac muscle force development rely on the regulation of both release (through channels or ryanodine receptors, RyR) and uptake (by an ATPase) of Ca2+ by the sarcoplasmic reticulum (SR). In this work, we propose an experimental model in which Ca2+ transport is simplified by using a thermodynamic approach to inhibit part of the cellular Ca2+ transporters but keeping functional the SR release and uptake as almost sole transporters. Instead of membrane excitation, electrically quiescent cells were stimulated with brief caffeine pulses (10 mM, 0.1 s duration). The method was tested experimentally and the results were compared to mathematical simulations performed by using a modified version of the mathematical model of Ca2+ cycling in cardiomyocytes previously proposed [1]. Results indicated that the experimental model is suitable to study properties of the SR-cytosol Ca2+ transport in intact cells without significant interference of other competing transporters (e.g. Na+/ Ca2+ exchanger)." @default.
- W137282726 created "2016-06-24" @default.
- W137282726 creator A5002657860 @default.
- W137282726 creator A5015556111 @default.
- W137282726 creator A5034087246 @default.
- W137282726 date "2007-01-01" @default.
- W137282726 modified "2023-10-16" @default.
- W137282726 title "Calcium release and uptake from the cardiac sarcoplasmic reticulum: Experimental and mathematical models" @default.
- W137282726 cites W1982140992 @default.
- W137282726 cites W2001498679 @default.
- W137282726 cites W2003251032 @default.
- W137282726 cites W2021622307 @default.
- W137282726 cites W2024650887 @default.
- W137282726 cites W2042646075 @default.
- W137282726 cites W2054225000 @default.
- W137282726 cites W2132561989 @default.
- W137282726 cites W2164931274 @default.
- W137282726 cites W2226437153 @default.
- W137282726 cites W4293179290 @default.
- W137282726 doi "https://doi.org/10.1007/978-3-540-74471-9_230" @default.
- W137282726 hasPublicationYear "2007" @default.
- W137282726 type Work @default.
- W137282726 sameAs 137282726 @default.
- W137282726 citedByCount "0" @default.
- W137282726 crossrefType "book-chapter" @default.
- W137282726 hasAuthorship W137282726A5002657860 @default.
- W137282726 hasAuthorship W137282726A5015556111 @default.
- W137282726 hasAuthorship W137282726A5034087246 @default.
- W137282726 hasConcept C105702510 @default.
- W137282726 hasConcept C113217602 @default.
- W137282726 hasConcept C114908165 @default.
- W137282726 hasConcept C12554922 @default.
- W137282726 hasConcept C131584629 @default.
- W137282726 hasConcept C134018914 @default.
- W137282726 hasConcept C158617107 @default.
- W137282726 hasConcept C163415756 @default.
- W137282726 hasConcept C178790620 @default.
- W137282726 hasConcept C181199279 @default.
- W137282726 hasConcept C185592680 @default.
- W137282726 hasConcept C191897082 @default.
- W137282726 hasConcept C192562407 @default.
- W137282726 hasConcept C201571599 @default.
- W137282726 hasConcept C2778500429 @default.
- W137282726 hasConcept C2778996579 @default.
- W137282726 hasConcept C519063684 @default.
- W137282726 hasConcept C55493867 @default.
- W137282726 hasConcept C86803240 @default.
- W137282726 hasConcept C98539663 @default.
- W137282726 hasConceptScore W137282726C105702510 @default.
- W137282726 hasConceptScore W137282726C113217602 @default.
- W137282726 hasConceptScore W137282726C114908165 @default.
- W137282726 hasConceptScore W137282726C12554922 @default.
- W137282726 hasConceptScore W137282726C131584629 @default.
- W137282726 hasConceptScore W137282726C134018914 @default.
- W137282726 hasConceptScore W137282726C158617107 @default.
- W137282726 hasConceptScore W137282726C163415756 @default.
- W137282726 hasConceptScore W137282726C178790620 @default.
- W137282726 hasConceptScore W137282726C181199279 @default.
- W137282726 hasConceptScore W137282726C185592680 @default.
- W137282726 hasConceptScore W137282726C191897082 @default.
- W137282726 hasConceptScore W137282726C192562407 @default.
- W137282726 hasConceptScore W137282726C201571599 @default.
- W137282726 hasConceptScore W137282726C2778500429 @default.
- W137282726 hasConceptScore W137282726C2778996579 @default.
- W137282726 hasConceptScore W137282726C519063684 @default.
- W137282726 hasConceptScore W137282726C55493867 @default.
- W137282726 hasConceptScore W137282726C86803240 @default.
- W137282726 hasConceptScore W137282726C98539663 @default.
- W137282726 hasLocation W1372827261 @default.
- W137282726 hasOpenAccess W137282726 @default.
- W137282726 hasPrimaryLocation W1372827261 @default.
- W137282726 hasRelatedWork W154292401 @default.
- W137282726 hasRelatedWork W1821931995 @default.
- W137282726 hasRelatedWork W1964255886 @default.
- W137282726 hasRelatedWork W1986273190 @default.
- W137282726 hasRelatedWork W2024858633 @default.
- W137282726 hasRelatedWork W2089232336 @default.
- W137282726 hasRelatedWork W2138310843 @default.
- W137282726 hasRelatedWork W2412710947 @default.
- W137282726 hasRelatedWork W2474136078 @default.
- W137282726 hasRelatedWork W4244267012 @default.
- W137282726 isParatext "false" @default.
- W137282726 isRetracted "false" @default.
- W137282726 magId "137282726" @default.
- W137282726 workType "book-chapter" @default.