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- W137368202 abstract "Publisher Summary This chapter examines the microassay of biogenic amines in neurons of Aplysia as well as the coexistence of more than one transmitter molecule in a neuron. The nervous system of Aplysia contains several giant cells that can be reproducibly identified on the basis of their size, position, pigmentation, and electrophysiological properties. Studies of these giant neurons reveal marked heterogeneity among this population of neurons in terms of their content of putative neurotransmitters. The unique occurrence in a particular neuron of either acetylcholine or serotonin and the enzymes required for their biosynthesis has traditionally been used to designate that neuron as either cholinergic or serotonergic, respectively. Moreover, these substances can be considered as putative neurotransmitters in invertebrates. These studies have been made possible because of the development of specific and sensitive enzymatic-isotopic micro-methods for the measurement of biogenic amines the concentration. Subsequently, the presence of several different neurotransmitters in single giant identified neurons of Aplysia suggests the possibility that Dale's principle may have to be re-evaluated when applied to these specific neurons." @default.
- W137368202 created "2016-06-24" @default.
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- W137368202 date "1978-01-01" @default.
- W137368202 modified "2023-09-27" @default.
- W137368202 title "MICROASSAY OF BIOGENIC AMINES IN NEURONS OF APLYSIA. THE COEXISTENCE OF MORE THAN ONE TRANSMITTER MOLECULE IN A NEURON" @default.
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- W137368202 doi "https://doi.org/10.1016/b978-0-08-021503-7.50014-5" @default.
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