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- W13739414 abstract "Administration of reserpine to rats completely abolished their secretion of growth hormone (GH). Administration of clonidine stimulated the GH secretion in reserpine-pre treated animals, whereas administration of apomorphine or 5-hydroxytryptophan was ineffective. Inhibition of the catecholamine synthesis by means of α-methyltyrosine partially suppressed the GH secretion, whereas inhibition of the synthesis of 5-hydroxytryptamine (5-HT) by means of p-chlorophenylalanine had no apparent effect. The results indicate that the reserpine-induced suppression of GH secretion in rats is mediated mainly by blockade of noradrenergic mechanisms and that the normal hormone secretion requires activation of noradrenaline (NA) receptors." @default.
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- W13739414 date "1979-01-01" @default.
- W13739414 modified "2023-10-16" @default.
- W13739414 title "CATECHOLAMINERGIC CONTROL OF GROWTH HORMONE SECRETION IN RATS" @default.
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- W13739414 doi "https://doi.org/10.1016/b978-1-4832-8363-0.50368-2" @default.
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