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W13740029 endingPage "2114" @default.
W13740029 startingPage "2084" @default.
W13740029 abstract "The outer retina is composed primarily of rod and cone photoreceptor (PR) cells and retina pigment epithelial cells. These cells serve as the main cells of the retina and initiate the process of phototransduction whereby light is converted and transmitted to the visual cortex of the brain to generate an image. The majority of the diseases of the outer retina are genetic (over 97%) and result from mutations in genes associated with photoreceptor development, phototransduction, and maintenance of normal photoreceptor function. The retinal pigment epithelium (RPE) functions to nourish the PR cells and provides a mechanism to recycle photoreceptor outer segments that are spent during phototransduction. Thus, mutations in RPE genes also cause outer retinal degeneration. Further, a small percentage of outer retinal diseases result from trauma or injury to the retina. This article provides an overview of the pathobiology of outer retinal diseases. While each case is unique, the biological processes that are disrupted are common and thus a common pathology primarily of rod and cone degeneration leads to debilitating vision loss." @default.
W13740029 created "2016-06-24" @default.
W13740029 creator A5029669589 @default.
W13740029 creator A5030036636 @default.
W13740029 creator A5033953081 @default.
W13740029 creator A5036770559 @default.
W13740029 date "2014-01-01" @default.
W13740029 modified "2023-09-26" @default.
W13740029 title "Pathobiology of the Outer Retina: Genetic and Nongenetic Causes of Disease" @default.
W13740029 cites W1125525217 @default.
W13740029 cites W127305701 @default.
W13740029 cites W135930319 @default.
W13740029 cites W1487528435 @default.
W13740029 cites W1490352649 @default.
W13740029 cites W1500193811 @default.
W13740029 cites W1507327514 @default.
W13740029 cites W1508022627 @default.
W13740029 cites W1515637235 @default.
W13740029 cites W1518382324 @default.
W13740029 cites W1530829742 @default.
W13740029 cites W1531022442 @default.
W13740029 cites W1544777143 @default.
W13740029 cites W1557009585 @default.
W13740029 cites W1565206912 @default.
W13740029 cites W1571786712 @default.
W13740029 cites W1576154026 @default.
W13740029 cites W1580792839 @default.
W13740029 cites W1587113887 @default.
W13740029 cites W159419684 @default.
W13740029 cites W1595325053 @default.
W13740029 cites W1599843882 @default.
W13740029 cites W1696340081 @default.
W13740029 cites W1799877731 @default.
W13740029 cites W180947891 @default.
W13740029 cites W1845093339 @default.
W13740029 cites W1868187718 @default.
W13740029 cites W187440223 @default.
W13740029 cites W1898328784 @default.
W13740029 cites W193528990 @default.
W13740029 cites W1964424550 @default.
W13740029 cites W1964753793 @default.
W13740029 cites W1965235603 @default.
W13740029 cites W1967387655 @default.
W13740029 cites W1968703962 @default.
W13740029 cites W1968805530 @default.
W13740029 cites W1970286448 @default.
W13740029 cites W1970335747 @default.
W13740029 cites W1970499339 @default.
W13740029 cites W1971642620 @default.
W13740029 cites W1971704829 @default.
W13740029 cites W1972631980 @default.
W13740029 cites W1972731291 @default.
W13740029 cites W1973950535 @default.
W13740029 cites W1974113099 @default.
W13740029 cites W1974832413 @default.
W13740029 cites W1976332795 @default.
W13740029 cites W1976808784 @default.
W13740029 cites W1976846514 @default.
W13740029 cites W1977808261 @default.
W13740029 cites W1977829186 @default.
W13740029 cites W1978790584 @default.
W13740029 cites W1979899019 @default.
W13740029 cites W1980969801 @default.
W13740029 cites W1981614795 @default.
W13740029 cites W1982231767 @default.
W13740029 cites W1982926671 @default.
W13740029 cites W1983264848 @default.
W13740029 cites W1984760582 @default.
W13740029 cites W1986170218 @default.
W13740029 cites W1986956890 @default.
W13740029 cites W1987186922 @default.
W13740029 cites W1989169885 @default.
W13740029 cites W1989551786 @default.
W13740029 cites W1989558725 @default.
W13740029 cites W1989747234 @default.
W13740029 cites W1990401322 @default.
W13740029 cites W1990914866 @default.
W13740029 cites W1991728641 @default.
W13740029 cites W1992190771 @default.
W13740029 cites W1993084414 @default.
W13740029 cites W1993087645 @default.
W13740029 cites W1993530603 @default.
W13740029 cites W1994071473 @default.
W13740029 cites W1994104925 @default.
W13740029 cites W1994717223 @default.
W13740029 cites W1994729397 @default.
W13740029 cites W1995797129 @default.
W13740029 cites W1996364002 @default.
W13740029 cites W1997255041 @default.
W13740029 cites W1997374942 @default.
W13740029 cites W1997761753 @default.
W13740029 cites W1998533469 @default.
W13740029 cites W1999361080 @default.
W13740029 cites W2000328536 @default.
W13740029 cites W2000662971 @default.
W13740029 cites W2001210978 @default.
W13740029 cites W2001720244 @default.
W13740029 cites W2002152165 @default.