Matches in SemOpenAlex for { <https://semopenalex.org/work/W137462118> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W137462118 endingPage "R347" @default.
- W137462118 startingPage "R341" @default.
- W137462118 abstract "We have reported that microinjection of angiotensin II (ANG II) into the nucleus tractus solitarius of urethan-anesthetized normotensive rats produces an increase in mean arterial pressure (MAP) over the dose range 50-500 pmol. The effect in spontaneously hypertensive rats (SHR) is now reported. Over the range 100-500 pmol SHR exhibit increases in MAP and heart rate greater than Wistar-Kyoto or Sprague-Dawley rats. SHR did not exhibit exaggerated responses to intravenous phenylephrine, suggesting a central site of increased responsiveness to ANG II. We also found depressor effects in Sprague-Dawley at lower doses (0.1 and 1 pmol). The decreases in MAP were extremely variable and not dose related. A selected dose of additional neuropeptides identified in the NTS was tested. Somatostatin, bradykinin, and vasoactive intestinal peptide (0.5 nmol) were without cardiovascular effects. Oxytocin and vasopressin, however, produced significant increases in MAP. Substance P produced a very small but significant increase in heart rate and MAP. Interaction between the vasopressin and ANG II pressor effects was studied, and each proved to be independent." @default.
- W137462118 created "2016-06-24" @default.
- W137462118 creator A5005095833 @default.
- W137462118 creator A5025593852 @default.
- W137462118 date "1985-09-01" @default.
- W137462118 modified "2023-10-18" @default.
- W137462118 title "Neuropeptide action in nucleus tractus solitarius: angiotensin specificity and hypertensive rats" @default.
- W137462118 doi "https://doi.org/10.1152/ajpregu.1985.249.3.r341" @default.
- W137462118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2931031" @default.
- W137462118 hasPublicationYear "1985" @default.
- W137462118 type Work @default.
- W137462118 sameAs 137462118 @default.
- W137462118 citedByCount "16" @default.
- W137462118 countsByYear W1374621182012 @default.
- W137462118 countsByYear W1374621182020 @default.
- W137462118 crossrefType "journal-article" @default.
- W137462118 hasAuthorship W137462118A5005095833 @default.
- W137462118 hasAuthorship W137462118A5025593852 @default.
- W137462118 hasConcept C118303440 @default.
- W137462118 hasConcept C126322002 @default.
- W137462118 hasConcept C134018914 @default.
- W137462118 hasConcept C170493617 @default.
- W137462118 hasConcept C185592680 @default.
- W137462118 hasConcept C198710026 @default.
- W137462118 hasConcept C2776176026 @default.
- W137462118 hasConcept C2776370428 @default.
- W137462118 hasConcept C2776452961 @default.
- W137462118 hasConcept C2777952589 @default.
- W137462118 hasConcept C2777953023 @default.
- W137462118 hasConcept C2779591629 @default.
- W137462118 hasConcept C2908929049 @default.
- W137462118 hasConcept C56191518 @default.
- W137462118 hasConcept C62525196 @default.
- W137462118 hasConcept C71315377 @default.
- W137462118 hasConcept C71924100 @default.
- W137462118 hasConcept C84393581 @default.
- W137462118 hasConceptScore W137462118C118303440 @default.
- W137462118 hasConceptScore W137462118C126322002 @default.
- W137462118 hasConceptScore W137462118C134018914 @default.
- W137462118 hasConceptScore W137462118C170493617 @default.
- W137462118 hasConceptScore W137462118C185592680 @default.
- W137462118 hasConceptScore W137462118C198710026 @default.
- W137462118 hasConceptScore W137462118C2776176026 @default.
- W137462118 hasConceptScore W137462118C2776370428 @default.
- W137462118 hasConceptScore W137462118C2776452961 @default.
- W137462118 hasConceptScore W137462118C2777952589 @default.
- W137462118 hasConceptScore W137462118C2777953023 @default.
- W137462118 hasConceptScore W137462118C2779591629 @default.
- W137462118 hasConceptScore W137462118C2908929049 @default.
- W137462118 hasConceptScore W137462118C56191518 @default.
- W137462118 hasConceptScore W137462118C62525196 @default.
- W137462118 hasConceptScore W137462118C71315377 @default.
- W137462118 hasConceptScore W137462118C71924100 @default.
- W137462118 hasConceptScore W137462118C84393581 @default.
- W137462118 hasIssue "3" @default.
- W137462118 hasLocation W1374621181 @default.
- W137462118 hasLocation W1374621182 @default.
- W137462118 hasOpenAccess W137462118 @default.
- W137462118 hasPrimaryLocation W1374621181 @default.
- W137462118 hasRelatedWork W137462118 @default.
- W137462118 hasRelatedWork W1974450177 @default.
- W137462118 hasRelatedWork W1981277940 @default.
- W137462118 hasRelatedWork W1984470734 @default.
- W137462118 hasRelatedWork W1998351332 @default.
- W137462118 hasRelatedWork W2065714688 @default.
- W137462118 hasRelatedWork W2072812615 @default.
- W137462118 hasRelatedWork W2072872068 @default.
- W137462118 hasRelatedWork W2088618831 @default.
- W137462118 hasRelatedWork W2407537258 @default.
- W137462118 hasVolume "249" @default.
- W137462118 isParatext "false" @default.
- W137462118 isRetracted "false" @default.
- W137462118 magId "137462118" @default.
- W137462118 workType "article" @default.