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- W137641214 abstract "Background – The mineral and organic acid components of plant foods make a contribution to the nutritionalquality of fruits and vegetables alongside other micro- and macronutrients that are studied more extensively. Thenutrient composition of many tropical crops has not been described in detail; in particular there is a lack ofinformation on mineral and organic acid components. In addition to content, the bioavailability of nutritionalcomponents needs to be determined in order to quantify likely effects of food on nutritional status. Here we report astudy of the release of minerals and organic acids during simulated digestion and subsequent uptake as mimicked byCaco-2 cell monolayers.Objective – The development of an in-vitro human mimetic model of digestion and absorption, and the study of therelease of minerals and organic acids from tropical fruits and their absorption in the small intestine.Design – Freeze-dried or raw samples of a range of tropical crops are cut into slices of 4g. An in-vitro mimic ofhuman digestion is used, comprising oral (human a-amylase 100 units/L, pH 6.9), gastric (porcine pepsin 800-2,500units/mg, pH 2), and pancreatic (pancreatin activity 4 X USP specification and bile extract, pH 6) digestion modelsfollowed by an in-vitro model of small intestine absorption using Caco-2 cell monolayers.Outcomes – Mineral and organic acid contents of a range of tropical crops, their release during simulated digestion,and their uptake by Caco-2 cells will be reported.Conclusion – This information will be useful in defining the opportunity for tropical crops to contribute to mineralnutrition. The potential for fruits and vegetables to be a prime source of balanced mineral nutrition opens up anunder-exploited opportunity for both food industry innovation and public health messages, through incorporation ofrelevant plant materials into a range of food products and provision of evidence for new marketing messagespromoting fresh produce" @default.
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- W137641214 date "2007-01-01" @default.
- W137641214 modified "2023-09-27" @default.
- W137641214 title "In-vitro model of mineral and organic acid absorption from tropical crops" @default.
- W137641214 hasPublicationYear "2007" @default.
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