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- W137656216 abstract "9581 Background: Complete pathology reporting of factors influencing local recurrence risk is essential for accurate staging and treatment planning in breast cancer. Pathologic assessment of tumor size, histologic grade, margin status, and extent of intraductal component may influence the decision to pursue additional treatment following breast conserving surgery. The American College of Pathologists (ACP) has published consensus guidelines for breast pathology reporting based on established prognostic and predictive factors. This study assessed differences in adherence to the ACP guidelines between tertiary-care and community-based hospital pathology departments. Methods: 250 consecutive surgical pathology reports were collected from one tertiary care and one community hospital. 195 demonstrating infiltrating or intraductal carcinoma were analyzed. Three reviewers, blinded to hospital of origin, independently scored each report for completeness based on the 1999 ACP guidelines. Differences by site were analyzed by t-tests and multivariate logistic regression. Results: 66 reports of invasive carcinoma, 38 reports of DCIS, and 91 reports of invasive carcinoma with a DCIS component were analyzed. Among invasive only cases, margin status was reported less often by university-based pathologists (p<0.01). For DCIS only, disease extent was reported significantly more often at the university (p<0.05); reporting of DCIS grade or necrosis did not vary. Results for cases of invasive carcinoma with DCIS are shown below: Conclusions: University pathology departments are more likely to quantify extent of tumor, but less likely to report margin status. Both university and community pathology departments underreport based on ACP guidelines. Failure to include prognostic information may lead to under-treatment and inaccurate perceptions of local recurrence risk. No significant financial relationships to disclose." @default.
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- W137656216 date "2004-07-15" @default.
- W137656216 modified "2023-09-27" @default.
- W137656216 title "Reporting of pathologic factors influencing local recurrence in ductal carcinoma in situ and invasive mammary carcinoma" @default.
- W137656216 doi "https://doi.org/10.1200/jco.2004.22.90140.9581" @default.
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