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- W137678329 abstract "Prolyl endopeptidase (PEP, EC 3.4.21.26), suggested to participate in learning and memory processes, has been reported to be abundant in brains of amnestic patients. Therefore, compounds possessing PEP inhibitory activity are expected to control memory loss and neuropathological disorders. Upon examination for PEP inhibition from dietary sources, polyunsaturated fatty acids were chosen, because they are essential fatty acids for normal brain and their deficiencies are linked to decreased memory and mental abilities. Docosahexaenoic acid [22:6 ] and eicosapentaenoic acid [20:5 ] showed similar PEP inhibitory activity with values of 21.8 () and , respectively. Diet high in essential polyunsaturated fatty acids may help decrease age-related memory loss." @default.
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- W137678329 date "2004-01-01" @default.
- W137678329 modified "2023-09-23" @default.
- W137678329 title "Prolyl Endopeptidase Inhibitory Activity of Omega-3 Polyunsaturated Fatty Acids" @default.
- W137678329 hasPublicationYear "2004" @default.
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