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• W13768249 endingPage "288" @default.
• W13768249 startingPage "270" @default.
• W13768249 abstract "Mast cells (MCs) were first described by Paul Ehrlich 1 in his doctoral thesis. MCs have long been implicated in the pathogenesis of allergic reactions and certain protective responses to parasites. As most tumors contain inflammatory cell infiltrates, which often include plentiful MCs, the question as to the possible contribution of MCs to tumor development has progressively been emerging. In this chapter, the specific involvement of MCs in tumor biology and tumor fate will be considered, with particular emphasis on the capacity of these cells to stimulate tumor growth by promoting angiogenesis and lymphangiogenesis. Data from experimental carcinogenesis and from different tumor settings in human pathology will be summarized. Information to be presented will suggest that MCs may serve as a novel therapeutic target for cancer treatment." @default.
• W13768249 created "2016-06-24" @default.
• W13768249 creator A5054370212 @default.
• W13768249 creator A5076861173 @default.
• W13768249 date "2011-01-01" @default.
• W13768249 modified "2023-10-16" @default.
• W13768249 title "Mast Cells, Angiogenesis and Cancer" @default.
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