Matches in SemOpenAlex for { <https://semopenalex.org/work/W137685235> ?p ?o ?g. }
- W137685235 endingPage "563" @default.
- W137685235 startingPage "557" @default.
- W137685235 abstract "Infection with the JHM strain of mouse hepatitis virus (JHMV) results in acute encephalomyelitis accompanied by primary demyelination in the central nervous system (CNS; 1) . Animals that survive show evidence of persistent viral infection in the CNS that is associated with ongoing demyelination (2). Infection of immunocompromised animals suggests that the immune response is important not only in survival, but also as a determinant of whether the infection is cleared or progresses to become persistent. We initially demonstrated that the addition of anti-viral antibody to in vitro cultures of cells persistently infected with JHMV stopped the release of infectious virus (3,4). These in vitro data suggested that anti-viral antibody might play an important role in the ability of JHMV to establish a persistent infection in the CNS. Subsequent work has demonstrated that the passive transfer of monoclonal antibodies specific for all three structural proteins prevents death due to acute infection (5,6,7,8). Two very surprising findings were made. First, none of the transferred antibodies inhibited the replication of the virus in the CNS." @default.
- W137685235 created "2016-06-24" @default.
- W137685235 creator A5039838353 @default.
- W137685235 creator A5050614600 @default.
- W137685235 creator A5058587157 @default.
- W137685235 creator A5087461838 @default.
- W137685235 date "1990-01-01" @default.
- W137685235 modified "2023-09-25" @default.
- W137685235 title "T Cell-Mediated Clearance of JHMV from the Central Nervous System" @default.
- W137685235 cites W1547943245 @default.
- W137685235 cites W1599476759 @default.
- W137685235 cites W1624339661 @default.
- W137685235 cites W1892022085 @default.
- W137685235 cites W1938874210 @default.
- W137685235 cites W1974967271 @default.
- W137685235 cites W1983158097 @default.
- W137685235 cites W1985246375 @default.
- W137685235 cites W2009364989 @default.
- W137685235 cites W2009787790 @default.
- W137685235 cites W2019442719 @default.
- W137685235 cites W2022942097 @default.
- W137685235 cites W2064590310 @default.
- W137685235 cites W2070683692 @default.
- W137685235 cites W2083873191 @default.
- W137685235 cites W94202725 @default.
- W137685235 doi "https://doi.org/10.1007/978-1-4684-5823-7_77" @default.
- W137685235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1966449" @default.
- W137685235 hasPublicationYear "1990" @default.
- W137685235 type Work @default.
- W137685235 sameAs 137685235 @default.
- W137685235 citedByCount "2" @default.
- W137685235 crossrefType "book-chapter" @default.
- W137685235 hasAuthorship W137685235A5039838353 @default.
- W137685235 hasAuthorship W137685235A5050614600 @default.
- W137685235 hasAuthorship W137685235A5058587157 @default.
- W137685235 hasAuthorship W137685235A5087461838 @default.
- W137685235 hasBestOaLocation W1376852351 @default.
- W137685235 hasConcept C126894567 @default.
- W137685235 hasConcept C138944611 @default.
- W137685235 hasConcept C140704245 @default.
- W137685235 hasConcept C142724271 @default.
- W137685235 hasConcept C159047783 @default.
- W137685235 hasConcept C159654299 @default.
- W137685235 hasConcept C169760540 @default.
- W137685235 hasConcept C203014093 @default.
- W137685235 hasConcept C2522874641 @default.
- W137685235 hasConcept C2776844884 @default.
- W137685235 hasConcept C2777648638 @default.
- W137685235 hasConcept C2777899865 @default.
- W137685235 hasConcept C2779134260 @default.
- W137685235 hasConcept C2779567548 @default.
- W137685235 hasConcept C2780640218 @default.
- W137685235 hasConcept C3008058167 @default.
- W137685235 hasConcept C524204448 @default.
- W137685235 hasConcept C529278444 @default.
- W137685235 hasConcept C542903549 @default.
- W137685235 hasConcept C71924100 @default.
- W137685235 hasConcept C86803240 @default.
- W137685235 hasConcept C8891405 @default.
- W137685235 hasConceptScore W137685235C126894567 @default.
- W137685235 hasConceptScore W137685235C138944611 @default.
- W137685235 hasConceptScore W137685235C140704245 @default.
- W137685235 hasConceptScore W137685235C142724271 @default.
- W137685235 hasConceptScore W137685235C159047783 @default.
- W137685235 hasConceptScore W137685235C159654299 @default.
- W137685235 hasConceptScore W137685235C169760540 @default.
- W137685235 hasConceptScore W137685235C203014093 @default.
- W137685235 hasConceptScore W137685235C2522874641 @default.
- W137685235 hasConceptScore W137685235C2776844884 @default.
- W137685235 hasConceptScore W137685235C2777648638 @default.
- W137685235 hasConceptScore W137685235C2777899865 @default.
- W137685235 hasConceptScore W137685235C2779134260 @default.
- W137685235 hasConceptScore W137685235C2779567548 @default.
- W137685235 hasConceptScore W137685235C2780640218 @default.
- W137685235 hasConceptScore W137685235C3008058167 @default.
- W137685235 hasConceptScore W137685235C524204448 @default.
- W137685235 hasConceptScore W137685235C529278444 @default.
- W137685235 hasConceptScore W137685235C542903549 @default.
- W137685235 hasConceptScore W137685235C71924100 @default.
- W137685235 hasConceptScore W137685235C86803240 @default.
- W137685235 hasConceptScore W137685235C8891405 @default.
- W137685235 hasLocation W1376852351 @default.
- W137685235 hasLocation W1376852352 @default.
- W137685235 hasOpenAccess W137685235 @default.
- W137685235 hasPrimaryLocation W1376852351 @default.
- W137685235 hasRelatedWork W1270582146 @default.
- W137685235 hasRelatedWork W1572227522 @default.
- W137685235 hasRelatedWork W172644496 @default.
- W137685235 hasRelatedWork W189766488 @default.
- W137685235 hasRelatedWork W1970441521 @default.
- W137685235 hasRelatedWork W2003416812 @default.
- W137685235 hasRelatedWork W2075226651 @default.
- W137685235 hasRelatedWork W2097978510 @default.
- W137685235 hasRelatedWork W2389269289 @default.
- W137685235 hasRelatedWork W2763118194 @default.
- W137685235 isParatext "false" @default.
- W137685235 isRetracted "false" @default.
- W137685235 magId "137685235" @default.