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- W138207192 abstract "This review describes approaches to the photoaffinity labeling of 2′,5′-oligoadenylate (2-5A) synthetase, RNase L, and p68 kinase employing azido probes with photolabile groups on carbon-2 or carbon-8 of adenine or inosine nucleotides. The covalent cross-linking of 2- or 8-azidoATP to 2-5A synthetase, 2- and 8-azido analogs of 2-5A to RNase L, and azido dsRNAs to 2-5A synthetase and p68 kinase is described. In addition, the newly discovered role of the 2-5A molecule as an inhibitor of HIV-l reverse transcriptase (RT) is discussed." @default.
- W138207192 created "2016-06-24" @default.
- W138207192 creator A5017043893 @default.
- W138207192 date "1994-01-01" @default.
- W138207192 modified "2023-10-17" @default.
- W138207192 title "Photolabeling of the Enzymes of the 2-5A Synthetase/RNase L/p68 Kinase Antiviral Systems with Azido Probes" @default.
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- W138207192 doi "https://doi.org/10.1007/978-3-642-78549-8_15" @default.
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