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- W13879552 abstract "After inoculation with JHM strain into DBT cell monolayers, a persistently infected DBT cell culture was established without producing typical cytopathic changes after about 15th passages. By immunofluorescence virus specific antigen was demonstrated in 10 to 15% DBT cells. This persistently infected culture (JHM-CC) was resistant to superinfection with parental JHM, but such resistance was not shown against vesicular stomatitis virus. JHM-CC virus produced small plaques on DBT cell monolayers. Temperature sensitive (TS) mutant, defective interfering (DI) particle or interferon was not detected in the JHM-CC. To intracerebral inoculation with JHM-CC virus, cortisone treated ICR mice survived without showing clinical signs, however, demyelinating lesions were produced in the brain and spinal cord of them." @default.
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- W13879552 date "1981-01-01" @default.
- W13879552 modified "2023-10-02" @default.
- W13879552 title "Persistent Infection with Mouse Hepatitis Virus, JHM Strain in DBT Cell Culture" @default.
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- W13879552 doi "https://doi.org/10.1007/978-1-4757-0456-3_24" @default.
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