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- W138860715 endingPage "197" @default.
- W138860715 startingPage "163" @default.
- W138860715 abstract "Vertebrate striated (skeletal and cardiac) muscle contraction is regulated in a Ca2+-dependent manner by the troponin (Tn) complex through interactions with tropomyosin (Tm) and the actin filament. The Tn complex consists of three proteins: troponin I (TnI) which inhibits the actomyosin Mg2+-ATPase activity, troponin C (TnC) which binds Ca2+ ions and removes TnI inhibition, and troponin T (TnT) which makes primary interaction with Tm. These three subunits interact in a cooperative manner with each other and with Tm and actin. Binding of Ca2+ to TnC initiates structural changes in TnC which lead to structural changes in the other Tn subunits (TnI and TnT) as well as Tm. The movement of Tm on the actin filament facilitates the interaction between myosin and actin leading to muscle contraction. The cation, Ca2+, is the main regulatory and signaling molecule in striated muscle. Another cation, Mg2+, is also important in the regulation of striated muscle contraction mainly via its ability to inhibit the Ca2+ release channel, especially in skeletal muscle." @default.
- W138860715 created "2016-06-24" @default.
- W138860715 creator A5061424503 @default.
- W138860715 creator A5070461651 @default.
- W138860715 creator A5074786555 @default.
- W138860715 date "2002-01-01" @default.
- W138860715 modified "2023-09-27" @default.
- W138860715 title "Cation Signaling in Striated Muscle Contraction" @default.
- W138860715 cites W1531580640 @default.
- W138860715 cites W1534652943 @default.
- W138860715 cites W1542758544 @default.
- W138860715 cites W1595932129 @default.
- W138860715 cites W1603386518 @default.
- W138860715 cites W1622559080 @default.
- W138860715 cites W1774036674 @default.
- W138860715 cites W1892398115 @default.
- W138860715 cites W1894073597 @default.
- W138860715 cites W1924552905 @default.
- W138860715 cites W1941910566 @default.
- W138860715 cites W1964192048 @default.
- W138860715 cites W1964334689 @default.
- W138860715 cites W1964432333 @default.
- W138860715 cites W1965571199 @default.
- W138860715 cites W1966972600 @default.
- W138860715 cites W1967356330 @default.
- W138860715 cites W1969749384 @default.
- W138860715 cites W1970195157 @default.
- W138860715 cites W1973150566 @default.
- W138860715 cites W1973587363 @default.
- W138860715 cites W1975559876 @default.
- W138860715 cites W1976711760 @default.
- W138860715 cites W1978555286 @default.
- W138860715 cites W1980004611 @default.
- W138860715 cites W1980612003 @default.
- W138860715 cites W1982988117 @default.
- W138860715 cites W1985654050 @default.
- W138860715 cites W1986038008 @default.
- W138860715 cites W1987846018 @default.
- W138860715 cites W1991181643 @default.
- W138860715 cites W1991564648 @default.
- W138860715 cites W1993055779 @default.
- W138860715 cites W1993783946 @default.
- W138860715 cites W1995280708 @default.
- W138860715 cites W1995319149 @default.
- W138860715 cites W1996140321 @default.
- W138860715 cites W1996427534 @default.
- W138860715 cites W1996858222 @default.
- W138860715 cites W1997057172 @default.
- W138860715 cites W1997577794 @default.
- W138860715 cites W2002538995 @default.
- W138860715 cites W2003599324 @default.
- W138860715 cites W2004767153 @default.
- W138860715 cites W2005432492 @default.
- W138860715 cites W2008983501 @default.
- W138860715 cites W2013195452 @default.
- W138860715 cites W2013272984 @default.
- W138860715 cites W2013730193 @default.
- W138860715 cites W2013958930 @default.
- W138860715 cites W2014559676 @default.
- W138860715 cites W2015963233 @default.
- W138860715 cites W2016053311 @default.
- W138860715 cites W2018747164 @default.
- W138860715 cites W2021726192 @default.
- W138860715 cites W2024662539 @default.
- W138860715 cites W2024929666 @default.
- W138860715 cites W2026880064 @default.
- W138860715 cites W2028094000 @default.
- W138860715 cites W2028507130 @default.
- W138860715 cites W2028682257 @default.
- W138860715 cites W2030312369 @default.
- W138860715 cites W2032894671 @default.
- W138860715 cites W2035320775 @default.
- W138860715 cites W2036756101 @default.
- W138860715 cites W2036861647 @default.
- W138860715 cites W2039365607 @default.
- W138860715 cites W2039544289 @default.
- W138860715 cites W2039932112 @default.
- W138860715 cites W2040179837 @default.
- W138860715 cites W2040389590 @default.
- W138860715 cites W2044629144 @default.
- W138860715 cites W2045050005 @default.
- W138860715 cites W2049403722 @default.
- W138860715 cites W2049504813 @default.
- W138860715 cites W2051018818 @default.
- W138860715 cites W2053478359 @default.
- W138860715 cites W2063109205 @default.
- W138860715 cites W2064515692 @default.
- W138860715 cites W2067142765 @default.
- W138860715 cites W2068251811 @default.
- W138860715 cites W2069953906 @default.
- W138860715 cites W2071824089 @default.
- W138860715 cites W2073815722 @default.
- W138860715 cites W2073883999 @default.
- W138860715 cites W2074639418 @default.
- W138860715 cites W2077757600 @default.
- W138860715 cites W2079498453 @default.
- W138860715 cites W2080955459 @default.
- W138860715 cites W2083616386 @default.