FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W139798664> ?p ?o ?g. }

• W139798664 abstract "Retinoic acid (RA), an active metabolite of dietary vitamin A (1,2), is essential to maintain normal growth and differentiation of epithelial cells (3,4). RA and certain of its analogs have also been used in experimental animals to prevent and treat cancers of a variety of epithelial tissues (4-9). The mode of action of RA remains speculative. Accumulating evidence indicate that RA mediates its effects through specific nuclear receptors (10-16). RA nuclear receptors belong to a super-family of steroid, thyroid and vitamin D receptors, the ligand-inducible transcriptional factors (10-12). Two major families of RA nuclear receptors (RAR and RXR) have been identified. The RAR (α,β, γ) are activated by both all trans-RA and 9-cis-RA while RXR (α, β, γ) are activated by 9-cis-RA only (16,17). Thus, RAR and RXR are distinct retinoid receptor subfamilies (16,17). RAR require co-regulators to bind effectively to RA responsive element (RARE) in a target gene. RXR functions as auxiliary receptor for RAR and related receptors (18). RXRI3 forms heterodimers with RAR to increase its DNA binding and transcriptional activity (16,19). Other transcriptional factors such as COUP-TF can also modulate RAR activities (20). We determined the role that RAR plays in the signal transduction pathway leading to the expression of tissue transglutaminase (TG) by RA (21,22). Data indicating that vitamin A nutritional status in rats influences the expression of both RAR and tissue TG in certain tissues will be presented. The results that imply that the levels of RAR determine the magnitude of tissue TG induction by retinoic acid will also be summarized." @default.
• W139798664 created "2016-06-24" @default.
• W139798664 creator A5028433789 @default.
• W139798664 creator A5070562109 @default.
• W139798664 date "1995-01-01" @default.
• W139798664 modified "2023-09-28" @default.
• W139798664 title "Involvement of Retinoic Acid Nuclear Receptors in Transcriptional Regulation of Tissue Transglutaminase, the Gene Involved in Apoptosis" @default.
• W139798664 cites W1493100105 @default.
• W139798664 cites W1578055894 @default.
• W139798664 cites W1714294326 @default.
• W139798664 cites W1762273637 @default.
• W139798664 cites W1799025303 @default.
• W139798664 cites W1858048976 @default.
• W139798664 cites W1892184508 @default.
• W139798664 cites W1895354212 @default.
• W139798664 cites W1896511711 @default.
• W139798664 cites W1981443985 @default.
• W139798664 cites W1987040411 @default.
• W139798664 cites W2003572799 @default.
• W139798664 cites W2008298934 @default.
• W139798664 cites W2008583255 @default.
• W139798664 cites W2012397917 @default.
• W139798664 cites W2015339616 @default.
• W139798664 cites W2022708373 @default.
• W139798664 cites W2030488757 @default.
• W139798664 cites W2043924374 @default.
• W139798664 cites W2047059548 @default.
• W139798664 cites W2051663421 @default.
• W139798664 cites W2053191064 @default.
• W139798664 cites W2056123411 @default.
• W139798664 cites W2061178138 @default.
• W139798664 cites W2080919477 @default.
• W139798664 cites W2082506663 @default.
• W139798664 cites W2083436346 @default.
• W139798664 cites W2085953550 @default.
• W139798664 cites W2097616503 @default.
• W139798664 cites W2097998324 @default.
• W139798664 cites W2120176836 @default.
• W139798664 cites W2125429880 @default.
• W139798664 cites W2166543236 @default.
• W139798664 cites W2173037214 @default.
• W139798664 doi "https://doi.org/10.1007/978-1-4612-0237-0_9" @default.
• W139798664 hasPublicationYear "1995" @default.
• W139798664 type Work @default.
• W139798664 sameAs 139798664 @default.
• W139798664 citedByCount "1" @default.
• W139798664 crossrefType "book-chapter" @default.
• W139798664 hasAuthorship W139798664A5028433789 @default.
• W139798664 hasAuthorship W139798664A5070562109 @default.
• W139798664 hasConcept C104317684 @default.
• W139798664 hasConcept C120197328 @default.
• W139798664 hasConcept C126322002 @default.
• W139798664 hasConcept C128821507 @default.
• W139798664 hasConcept C134018914 @default.
• W139798664 hasConcept C162253465 @default.
• W139798664 hasConcept C170493617 @default.
• W139798664 hasConcept C178498320 @default.
• W139798664 hasConcept C181199279 @default.
• W139798664 hasConcept C2775954498 @default.
• W139798664 hasConcept C2781121885 @default.
• W139798664 hasConcept C55493867 @default.
• W139798664 hasConcept C62478195 @default.
• W139798664 hasConcept C63932345 @default.
• W139798664 hasConcept C68484354 @default.
• W139798664 hasConcept C71924100 @default.
• W139798664 hasConcept C86339819 @default.
• W139798664 hasConcept C86803240 @default.
• W139798664 hasConcept C95444343 @default.
• W139798664 hasConceptScore W139798664C104317684 @default.
• W139798664 hasConceptScore W139798664C120197328 @default.
• W139798664 hasConceptScore W139798664C126322002 @default.
• W139798664 hasConceptScore W139798664C128821507 @default.
• W139798664 hasConceptScore W139798664C134018914 @default.
• W139798664 hasConceptScore W139798664C162253465 @default.
• W139798664 hasConceptScore W139798664C170493617 @default.
• W139798664 hasConceptScore W139798664C178498320 @default.
• W139798664 hasConceptScore W139798664C181199279 @default.
• W139798664 hasConceptScore W139798664C2775954498 @default.
• W139798664 hasConceptScore W139798664C2781121885 @default.
• W139798664 hasConceptScore W139798664C55493867 @default.
• W139798664 hasConceptScore W139798664C62478195 @default.
• W139798664 hasConceptScore W139798664C63932345 @default.
• W139798664 hasConceptScore W139798664C68484354 @default.
• W139798664 hasConceptScore W139798664C71924100 @default.
• W139798664 hasConceptScore W139798664C86339819 @default.
• W139798664 hasConceptScore W139798664C86803240 @default.
• W139798664 hasConceptScore W139798664C95444343 @default.
• W139798664 hasLocation W1397986641 @default.
• W139798664 hasOpenAccess W139798664 @default.
• W139798664 hasPrimaryLocation W1397986641 @default.
• W139798664 hasRelatedWork W111400266 @default.
• W139798664 hasRelatedWork W1239074664 @default.
• W139798664 hasRelatedWork W1564211606 @default.
• W139798664 hasRelatedWork W2003318378 @default.
• W139798664 hasRelatedWork W2003589824 @default.
• W139798664 hasRelatedWork W2053411409 @default.
• W139798664 hasRelatedWork W2065175731 @default.
• W139798664 hasRelatedWork W2082830386 @default.
• W139798664 hasRelatedWork W2095218122 @default.
• W139798664 hasRelatedWork W2099334382 @default.

• next