Matches in SemOpenAlex for { <https://semopenalex.org/work/W140499992> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W140499992 endingPage "381" @default.
- W140499992 startingPage "378" @default.
- W140499992 abstract "Postoperative heparin rebound was investigated in 50 adult patients undergoing cardiopulmonary bypass with the use of the Hepcon heparin analyzer. Prior to bypass each patient received 2 mg / kg of heparin. During bypass, the activated clotting time (ACT) was utilized to assess the need for additional heparin to maintain the value between 300 and 400 seconds. The average amount of heparin given was 160 mg. Once cardiopulmonary bypass was terminated the Hepcon unit was employed to determine the actual amount of active circulating heparin and to calculate the dose of protamine sulfate. The average amount of protamine administered intraoperatively was 200 mg. The overall mean ratio of protamine-to-heparin was 1.25:1. Once hemostasis was achieved, no circulating heparin was measured with the Hepcon unit, and the ACT value had returned to its baseline, the incisions were closed and the patients were transferred to the intensive care unit. One hour later a blood sample was obtained and analyzed by the Hepcon unit for any heparin rebound. We found that 26 patients (52%) had circulating heparin and required an additional dose of protamine, averaging 70 mg. Drainage from the thoracotomy tubes averaged 400 cc in the first 24 hours, and a mean of 2 units of packed cells was infused. Three patients (6%) did not require any blood transfusions. The use of the Hepcon unit has produced a safe and expedient method of analyzing and neutralizing active circulating heparin in patients following cardiopulmonary bypass. It is a useful adjunct in blood conservation because it reduces excessive postoperative blood loss associated with heparin rebound." @default.
- W140499992 created "2016-06-24" @default.
- W140499992 creator A5000190531 @default.
- W140499992 creator A5018948219 @default.
- W140499992 creator A5035652808 @default.
- W140499992 creator A5040347721 @default.
- W140499992 creator A5069514552 @default.
- W140499992 creator A5075456252 @default.
- W140499992 date "1981-03-01" @default.
- W140499992 modified "2023-09-29" @default.
- W140499992 title "Management of postoperative heparin rebound following cardiopulmonary bypass" @default.
- W140499992 cites W1451026943 @default.
- W140499992 cites W1975425465 @default.
- W140499992 cites W1989940253 @default.
- W140499992 cites W2000873042 @default.
- W140499992 cites W2063342678 @default.
- W140499992 cites W2077115398 @default.
- W140499992 cites W2157617856 @default.
- W140499992 cites W2415773543 @default.
- W140499992 cites W2416792871 @default.
- W140499992 doi "https://doi.org/10.1016/s0022-5223(19)37601-9" @default.
- W140499992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7464201" @default.
- W140499992 hasPublicationYear "1981" @default.
- W140499992 type Work @default.
- W140499992 sameAs 140499992 @default.
- W140499992 citedByCount "58" @default.
- W140499992 countsByYear W1404999922012 @default.
- W140499992 countsByYear W1404999922014 @default.
- W140499992 countsByYear W1404999922018 @default.
- W140499992 countsByYear W1404999922020 @default.
- W140499992 countsByYear W1404999922023 @default.
- W140499992 crossrefType "journal-article" @default.
- W140499992 hasAuthorship W140499992A5000190531 @default.
- W140499992 hasAuthorship W140499992A5018948219 @default.
- W140499992 hasAuthorship W140499992A5035652808 @default.
- W140499992 hasAuthorship W140499992A5040347721 @default.
- W140499992 hasAuthorship W140499992A5069514552 @default.
- W140499992 hasAuthorship W140499992A5075456252 @default.
- W140499992 hasConcept C141071460 @default.
- W140499992 hasConcept C2777557582 @default.
- W140499992 hasConcept C2777987278 @default.
- W140499992 hasConcept C2778589496 @default.
- W140499992 hasConcept C2778881276 @default.
- W140499992 hasConcept C2779354726 @default.
- W140499992 hasConcept C2780835560 @default.
- W140499992 hasConcept C42219234 @default.
- W140499992 hasConcept C71924100 @default.
- W140499992 hasConceptScore W140499992C141071460 @default.
- W140499992 hasConceptScore W140499992C2777557582 @default.
- W140499992 hasConceptScore W140499992C2777987278 @default.
- W140499992 hasConceptScore W140499992C2778589496 @default.
- W140499992 hasConceptScore W140499992C2778881276 @default.
- W140499992 hasConceptScore W140499992C2779354726 @default.
- W140499992 hasConceptScore W140499992C2780835560 @default.
- W140499992 hasConceptScore W140499992C42219234 @default.
- W140499992 hasConceptScore W140499992C71924100 @default.
- W140499992 hasIssue "3" @default.
- W140499992 hasLocation W1404999921 @default.
- W140499992 hasLocation W1404999922 @default.
- W140499992 hasOpenAccess W140499992 @default.
- W140499992 hasPrimaryLocation W1404999921 @default.
- W140499992 hasRelatedWork W140499992 @default.
- W140499992 hasRelatedWork W206436102 @default.
- W140499992 hasRelatedWork W2070599447 @default.
- W140499992 hasRelatedWork W2122521002 @default.
- W140499992 hasRelatedWork W2136807780 @default.
- W140499992 hasRelatedWork W2497634351 @default.
- W140499992 hasRelatedWork W3080585104 @default.
- W140499992 hasRelatedWork W4386383650 @default.
- W140499992 hasRelatedWork W96823224 @default.
- W140499992 hasRelatedWork W2049455104 @default.
- W140499992 hasVolume "81" @default.
- W140499992 isParatext "false" @default.
- W140499992 isRetracted "false" @default.
- W140499992 magId "140499992" @default.
- W140499992 workType "article" @default.