Matches in SemOpenAlex for { <https://semopenalex.org/work/W1410716927> ?p ?o ?g. }
- W1410716927 endingPage "443" @default.
- W1410716927 startingPage "429" @default.
- W1410716927 abstract "Publisher Summary This chapter reviews that modeling of the basal ganglia network in the late 1980s and early 1990s played an important role in generating and consolidating ideas about basal ganglia function. These models led to predictions about relationships between changes in striatal activity and alterations tonic firing rate in basal ganglia circuits, and triggered research that has evolved to show that firing pattern as well as rate contribute to the functional dynamics of normal and pathological activity in basal ganglia circuits. It discusses that under some conditions synchronized oscillatory neuronal activity in ultraslow, slow and faster frequency ranges are observed in basal ganglia circuits. As synchronized activity has enhanced impact on postsynaptic structures, these oscillations are useful tools for probing basal ganglia function as well as assessing functional connectivity within and between the basal ganglia nuclei and downstream sites. They may also provide insight into mechanisms underlying disease-related processes in the basal ganglia. The observation that removal of dopaminergic input or administration of dopamine agonists alters not only firing rates in the basal ganglia network, but also the extent of synchronization of oscillatory firing patterns may constitute important insight into processes underlying the symptomology of Parkinson's disease. The processes regulating synchronized and oscillatory activity in the basal ganglia, the role of these patterns in normal basal ganglia function and the mechanisms underlying the ability of neuromodulators like dopamine to regulate the transmission of these patterns through basal ganglia circuits are not yet well understood and provide opportunities for research endeavors in the coming decade." @default.
- W1410716927 created "2016-06-24" @default.
- W1410716927 creator A5034511392 @default.
- W1410716927 creator A5042611495 @default.
- W1410716927 date "2010-01-01" @default.
- W1410716927 modified "2023-09-23" @default.
- W1410716927 title "Synchronous Activity in Basal Ganglia Circuits" @default.
- W1410716927 cites W14452170 @default.
- W1410716927 cites W1498617277 @default.
- W1410716927 cites W1510554078 @default.
- W1410716927 cites W1516646705 @default.
- W1410716927 cites W1577374871 @default.
- W1410716927 cites W1590565925 @default.
- W1410716927 cites W1592587113 @default.
- W1410716927 cites W1592880753 @default.
- W1410716927 cites W1602855037 @default.
- W1410716927 cites W1768450208 @default.
- W1410716927 cites W1791046118 @default.
- W1410716927 cites W1832682301 @default.
- W1410716927 cites W1883604772 @default.
- W1410716927 cites W1901421707 @default.
- W1410716927 cites W1912943106 @default.
- W1410716927 cites W1927501767 @default.
- W1410716927 cites W1960975817 @default.
- W1410716927 cites W1965108138 @default.
- W1410716927 cites W1965628921 @default.
- W1410716927 cites W1966256648 @default.
- W1410716927 cites W1966577272 @default.
- W1410716927 cites W1966662050 @default.
- W1410716927 cites W1967863035 @default.
- W1410716927 cites W1970140591 @default.
- W1410716927 cites W1970695058 @default.
- W1410716927 cites W1971181257 @default.
- W1410716927 cites W1971283363 @default.
- W1410716927 cites W1978385183 @default.
- W1410716927 cites W1978491570 @default.
- W1410716927 cites W1979637630 @default.
- W1410716927 cites W1979673903 @default.
- W1410716927 cites W1980521160 @default.
- W1410716927 cites W1982827121 @default.
- W1410716927 cites W1983725026 @default.
- W1410716927 cites W1984035232 @default.
- W1410716927 cites W1985695713 @default.
- W1410716927 cites W1987526284 @default.
- W1410716927 cites W1987971960 @default.
- W1410716927 cites W1989193138 @default.
- W1410716927 cites W1990454524 @default.
- W1410716927 cites W1991603311 @default.
- W1410716927 cites W1991857015 @default.
- W1410716927 cites W1993984856 @default.
- W1410716927 cites W1996032190 @default.
- W1410716927 cites W1996524365 @default.
- W1410716927 cites W1998468025 @default.
- W1410716927 cites W2004028584 @default.
- W1410716927 cites W2005269174 @default.
- W1410716927 cites W2006807981 @default.
- W1410716927 cites W2009494091 @default.
- W1410716927 cites W2010705737 @default.
- W1410716927 cites W2012062329 @default.
- W1410716927 cites W2013468174 @default.
- W1410716927 cites W2013700750 @default.
- W1410716927 cites W2016696802 @default.
- W1410716927 cites W2017948121 @default.
- W1410716927 cites W2017949567 @default.
- W1410716927 cites W2018191142 @default.
- W1410716927 cites W2018553838 @default.
- W1410716927 cites W2020732236 @default.
- W1410716927 cites W2020925019 @default.
- W1410716927 cites W2021683549 @default.
- W1410716927 cites W2022072305 @default.
- W1410716927 cites W2022520344 @default.
- W1410716927 cites W2024154387 @default.
- W1410716927 cites W2024347935 @default.
- W1410716927 cites W2026640911 @default.
- W1410716927 cites W2027559291 @default.
- W1410716927 cites W2028373322 @default.
- W1410716927 cites W2031170958 @default.
- W1410716927 cites W2031914919 @default.
- W1410716927 cites W2039320104 @default.
- W1410716927 cites W2039381332 @default.
- W1410716927 cites W2040241220 @default.
- W1410716927 cites W2040312196 @default.
- W1410716927 cites W2045289490 @default.
- W1410716927 cites W2045379285 @default.
- W1410716927 cites W2046361830 @default.
- W1410716927 cites W2046717384 @default.
- W1410716927 cites W2047094285 @default.
- W1410716927 cites W2047575016 @default.
- W1410716927 cites W2048317486 @default.
- W1410716927 cites W2050567029 @default.
- W1410716927 cites W2051536308 @default.
- W1410716927 cites W2051572005 @default.
- W1410716927 cites W2051703627 @default.
- W1410716927 cites W2052142868 @default.
- W1410716927 cites W2056109168 @default.
- W1410716927 cites W2056807796 @default.
- W1410716927 cites W2057727146 @default.
- W1410716927 cites W2057788173 @default.