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- W141227006 abstract "Angiotensin-converting enzyme is present in the male reproductive system but its role in the physiology of reproduction is not known. To see the effect of angiotensin-converting enzyme on spermatozoal functions, lisinopril, an angiotensin-converting enzyme inhibitor, was administered orally using two different doses (10 and 20 mg/kg/day) to rats. Both short-term (2 weeks) and long-term (6 weeks) effects of the drug were observed. Lisinopril treatment resulted in a marked decrease in sperm density, sperm motility and zona pellucida penetration. Acrosome reaction by spermatozoa obtained from drug-treated animals was significantly lower when compared with spermatozoa from normal animals." @default.
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- W141227006 date "2000-01-01" @default.
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- W141227006 title "Role of angiotensin-converting enzyme inhibitor, lisinopril, on spermatozoal functions in rats" @default.
- W141227006 doi "https://doi.org/10.1358/mf.2000.22.3.796102" @default.
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