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- W1412352652 abstract "Publisher Summary This chapter discusses the organization of descending serotonergic projections to the spinal cord. The indolamine serotonin is believed to have important neurotransmitter and/or neuroregulatory roles in the descending pathways influencing various somatosensory, motor, and autonomic functions within the spinal cord. The autonomic preganglionic neurons of the thoracic spinal cord, as well as the motoneurons of the ventral horn, are also under the influence of descending serotonergic cell groups. Cells in these various motoneuron pools can be inhibited and/or excited by iontophoretic application of serotonin or by electrical stimulation of the descending serotonergic pathways. In recent years, the introduction of immunocytochemistry to neurobiology has provided a very sensitive method for studying the organization of descending serotonergic pathways. In contrast to the previously employed histofluorescence methods with which rapid photodecom-position of the yellow fluorescing cells and terminals was a constant problem, the peroxidase-antiperoxidase (PAP) immunochemical method results in a relatively permanent marker for 5-HT neurons and terminals." @default.
- W1412352652 created "2016-06-24" @default.
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- W1412352652 date "1982-01-01" @default.
- W1412352652 modified "2023-10-16" @default.
- W1412352652 title "Organization of Descending Serotonergic Projections to the Spinal Cord" @default.
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- W1412352652 doi "https://doi.org/10.1016/s0079-6123(08)64132-1" @default.
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