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- W1412814235 abstract "Leigh's disease (subacute necrotizing encephalopathy) is a neurometabolic disorder that typically manifests in young children. It is characterized by cognitive and neuromotor regression and ocular motor abnormalities. Extrapyramidal features and seizures may occur. Although etiologically diverse, a fundamental failure of energy metabolism characterizes patients with Leigh's syndrome. Treatment is largely supportive; although a ‘mitochondrial cocktail’ is often employed, outcomes are variable." @default.
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- W1412814235 date "2014-01-01" @default.
- W1412814235 modified "2023-10-16" @default.
- W1412814235 title "Subacute Necrotizing Encephalomyelopathy" @default.
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- W1412814235 doi "https://doi.org/10.1016/b978-0-12-385157-4.01053-8" @default.
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