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- W14136538 abstract "ABSTRACT Somatic cell hybrids between BW5147, a low metastatic AKR/J spontaneous thymoma and lymphocytes from H-2 d mice have been analysed for their tumorogenic and metastatic properties. Every hybrid line tested appeared to be more malignant than the BW5147 cells and acquired the capacity to produce spontaneous and experimental metastases. Uncloned hybridoma cells, when transplanted into recipient F1 mice, produced massive metastases in the liver, spleen, kidneys, lungs and meninges. Out of the meninges-seeking hybridomas we could derive variants that proliferated preferentially in the meninges. Preliminary analysis reveals that the meninges-seeking hybrid clones differ from their parental cells and other hybridomas in their membrane viscosity and content of Fc receptors for immunoglobulins." @default.
- W14136538 created "2016-06-24" @default.
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- W14136538 date "1982-01-01" @default.
- W14136538 modified "2023-10-16" @default.
- W14136538 title "CHANGES IN TUMOROGENIC AND METASTATIC PATTERN OF THYMOMA CELLS INDUCED BY THEIR HYBRIDIZATION TO NORMAL LYMPHOCYTES" @default.
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- W14136538 doi "https://doi.org/10.1016/b978-0-12-722380-3.50047-7" @default.
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