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- W1420524116 abstract "目的：探讨心脑通络液对动脉粥样硬化兔平滑肌细胞的干预作用。方法：选取健康雄性新西兰大耳兔40只。随机分成假手术组、模型组、血脂康组、心脑通络液高、低剂量组，对除假手术组外的其余组动物建立腹主动脉粥样硬化模型。造模成功后，各组分别灌胃给药，连续治疗8周，采用SP法测定各组家兔Bcl-2、Caspase-3的阳性表达率。结果：与假手术组比较，模型组Bcl-2含量明显降低，Casapase-3含量明显升高，差异有统计学意义（P〈0．05）；与模型组比较，血脂康组和高低剂量组Bcl-2含量均增高、Caspase-3含量均降低（P〈0．05），以高剂量改善最显著（P〈0．05）。结论：心脑通络液可能通过对bcl-2及Caspase-3蛋白表达的调控而降低动脉斑块内过度凋亡的平滑肌细胞，从而抑制粥样斑块的形成。" @default.
- W1420524116 created "2016-06-24" @default.
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- W1420524116 date "2014-01-01" @default.
- W1420524116 modified "2023-09-24" @default.
- W1420524116 title "心脑通络液对动脉粥样硬化兔平滑肌细胞Bcl-2、Caspase-3的影响" @default.
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